Monoaminergic Modulation of Cortical Excitability (eBook)

Marco Atzori, Kuei-Yuan Tseng (Herausgeber)

eBook Download: PDF

2007 | 2007
X, 329 Seiten
Springer US (Verlag)
978-0-387-72256-6 (ISBN)

Infos

This book provides a comprehensive, integrated comparison of the complex modulatory action of dopamine, noradrenaline, and serotonin receptors in the cortex. The discussion assembles a range of opinions on how the monoamine systems affect cortical function. The complexity of these interactions is discussed in light of recent data showing the dramatic effect of disruption of these systems on memory formation and information processing in the cortex.

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Monoaminergic Modulation of Cortical Excitability serves as an integrative and comprehensive comparison of the diverse and complex modulatory action of dopamine, noradrenaline, and serotonin receptors in the cortex. The volume is organized into several sections offering a broad spectrum of opinions on how the monoamine systems affect cortical function from a cellular/sub-cellular level to a system level. The complexity of these interactions are discussed in light of recent data showing how disruption of these systems dramatically affects the memory formation and information processing in the cortex.About the Editors:Dr. Kuei Y. Tseng is Assistant Professor in the Department of Cellular and Molecular Pharmacology at Rosalind Franklin University of Medicine and Science, The Chicago Medical School, North Chicago, IL, USA. Dr. Marco Atzori is Assistant Professor at the School for Behavioral and Brain Sciences at the University of Texas, Dallas, TX, USA.

Inhalt

Preface 5
Contents 6
The Discovery of Multiple Serotonin Receptor Subtypes: A Lesson from Molecular Cloning to Functional Expression 9
Distribution of D1-Like and D2 Receptors in the Monkey Brain: Implications for Cognitive Function in Schizophrenia 29
Anatomical Characteristics of Norepinephrine Axons in the Prefrontal Cortex: Unexpected Findings That May Indicate Low Activity State in Naïve Animals 42
Serotonin Modulation of Cortical Activity 73
Serotonergic Regulation of NMDA Receptor Trafficking and Function in Prefrontal Cortex 96
Cross-Modulation Between GABAB and 5-HT Receptors: A Link Between Anxiety and Depression? 107
Serotonin Involvement in Plasticity of the Visual Cortex 116
Cellular Mechanisms of Working Memory and its Modulation by Dopamine in the Prefrontal Cortex of Primates and Rats 128
Dopamine D1 and Glutamate N-Methyl-D-Aspartate Receptors: An Essential Interplay in Prefrontal Cortex Synaptic Plasticity 156
Prefrontal Cortical Synaptic Plasticity: The Roles of Dopamine and Implication for Schizophrenia 168
Acquiring the Excitatory and the Inhibitory Action of Dopamine in the Prefrontal Cortex During Postnatal Development 178
Dopamine and Noradrenaline Coupling in the Cerebral Cortex 191
Regulation of Cortical Functions by the Central Noradrenergic System: Emerging Properties from an Old Friend 199
Neuromodulation of Cortical Synaptic Plasticity 210
Dopaminergic Modulation of Prefrontal Cortex Network Dynamics 218
Stable and Unstable Activation of the Prefrontal Cortex with Dopaminergic Modulation 236
Dopamine and Norepinephrine Modulation of Cortical and Subcortical Dynamics During Visuomotor Learning 248
Basal Ganglia – Cortex Interactions: Regulation of Cortical Function by D1 Dopamine Receptors in the Striatum 262
Interplay Between Dopamine and Acetylcholine in the Modulation of Attention 284
Monoamine-Based Treatments in Schizophrenia: Time to Change the Paradigm? 299
Prefrontal Cortical Circuits and Schizophrenia Pathophysiology 313
Index 327

Produkt-Details

• Erscheint lt. Verlag: 24.8.2007
• Zusatzinfo: X, 329 p. 58 illus., 3 illus. in color.
• Verlagsort: New York
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Humanbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• Themenwelt: Technik
• Schlagworte: Cortex • cortical function • dopaminergic • monoamines • Physiology • prefrontal cortex • receptor • Seratonin • Visual cortex
• ISBN-10: 0-387-72256-4 / 0387722564
• ISBN-13: 978-0-387-72256-6 / 9780387722566