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Twenty Years of G-CSF

Clinical and Nonclinical Discoveries
Buch | Hardcover
XXII, 478 Seiten
2012 | 2012
Springer Basel (Verlag)
978-3-0348-0217-8 (ISBN)

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Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting.

This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and nononcology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF.

Basic Science.- Use of rHuG-CSF in the Oncology Setting.- Use of rHuG-CSF in Non-Oncology Setting.- Safety and Economics.- The Next 20 Years.

Erscheint lt. Verlag 7.1.2012
Reihe/Serie Milestones in Drug Therapy
Zusatzinfo XXII, 478 p.
Verlagsort Basel
Sprache englisch
Maße 155 x 235 mm
Gewicht 900 g
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte Hematopoiesis • Infectious Diseases • Neutropenia • Oncology • pharmacology
ISBN-10 3-0348-0217-X / 303480217X
ISBN-13 978-3-0348-0217-8 / 9783034802178
Zustand Neuware
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