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Twenty Years of G-CSF -

Twenty Years of G-CSF

Clinical and Nonclinical Discoveries
Buch | Softcover
XXII, 478 Seiten
2014 | 2012
Springer Basel (Verlag)
978-3-0348-0804-0 (ISBN)
CHF 307,95 inkl. MwSt
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This volume in the Milestones in Drug Therapy series describes the past 20 years of treatment with recombinant human G-CSF, including basic science, the use of G-CSF in both the oncology and non-oncology settings, and the safety and economics of its use.

Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting.

This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and nononcology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF.

Basic Science.- Use of rHuG-CSF in the Oncology Setting.- Use of rHuG-CSF in Non-Oncology Setting.- Safety and Economics.- The Next 20 Years.

Erscheint lt. Verlag 22.2.2014
Reihe/Serie Milestones in Drug Therapy
Zusatzinfo XXII, 478 p.
Verlagsort Basel
Sprache englisch
Maße 155 x 235 mm
Gewicht 759 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
Schlagworte Hematopoiesis • Infectious Diseases • Neutropenia • Oncology • pharmacology
ISBN-10 3-0348-0804-6 / 3034808046
ISBN-13 978-3-0348-0804-0 / 9783034808040
Zustand Neuware
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