Amino-Acid Homopolymers Occurring in Nature

Yoshimitsu Hamano (Herausgeber)

Buch | Hardcover

VII, 250 Seiten

2010 | 2010
Springer Berlin (Verlag)
978-3-642-12452-5 (ISBN)

Infos

Microorganisms are capable of producing a wide variety of biopolymers. Homopolymer peptides, which are made up of only a single type of amino acid, are far less ubiquitous. The only two amino-acid homopolymers known to occur in nature are presented in this volume.Poly-epsilon-L-lysine is a polycationic peptide and exhibits antimicrobial activity against a wide spectrum of microorganisms. It is both safe and biodegradable and is therefore used as a food preservative in several countries. In addition, there has been great interest in medical and other applications of poly-lysine and its derivatives.In contrast, poly-gamma-glutamic acid is an unusual anionic polypeptide. It is also water soluble, biodegradable, edible, non-toxic and non-immunogenic and can be chemically modified to introduce various drugs. These features are very useful for pharmaceutical and biomedical applications. Poly-glutamic acid is also a highly attractive as a food ingredient.

Inhalt

Occurrence and Production of Poly-Epsilon-l-Lysine in Microorganisms.- Biochemistry and Enzymology of Poly-Epsilon-l-Lysine Biosynthesis.- Biochemistry and Enzymology of Poly-Epsilon-l-Lysine Degradation.- Biotechnological Production of Poly-Epsilon-l-Lysine for Food and Medical Applications.- Occurrence and Biosynthetic Mechanism of Poly-Gamma-Glutamic Acid.- Enzymatic Degradation of Poly-Gamma-Glutamic Acid.- Pharmaceutical and Medical Applications of Poly-Gamma-Glutamic Acid.- Food Applications of Poly-Gamma-Glutamic Acid.

Produkt-Details

• Erscheint lt. Verlag: 16.7.2010
• Reihe/Serie: Microbiology Monographs
• Zusatzinfo: VII, 250 p. 62 illus.
• Verlagsort: Berlin
• Sprache: englisch
• Maße: 155 x 235 mm
• Gewicht: 471 g
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Schlagworte: Amino acid • biochemistry • biopolymers • Glutamic acid • Lysine • Microorganism • Polyaminoacids
• ISBN-10: 3-642-12452-6 / 3642124526
• ISBN-13: 978-3-642-12452-5 / 9783642124525
• Zustand: Neuware