Glycosaminoglycans in Development, Health and Disease
Academic Press Inc (Verlag)
978-0-12-381282-7 (ISBN)
Glycosaminoglycans (GAGs) are a family of linear polysaccharides that are found in all animal tissues. Several are used as biomaterials, including heparin, heparin sulfate, keratan sulfate, dermatan sulfate, and chondroitin sulfate.
This volume discusses the role of GAGs in development, health and disease.
Lijuan Zhang is a Professor of Translational Medicine at Ocean University of China. She completed her doctorates of biochemistry and molecular genetics at University of Alabama at Birmingham in 1995. Before then, she was a Fogarty International Fellow at NIH for three years studying glycan-based cancer biomarkers. She worked as post-doctorate fellow and research associate at both MIT and Harvard Medical School from 1995-2002. She joined the faculty of the Department of Pathology & Immunology at Washington University in St. Louis in 2002 as a tenure-tracked Assistant Professor. Her research had been focused on the biosynthesis, structures, and biological functions of glycans since 1985. Now her work is on translational aspects of glycans as biomarkers and therapeutics. She has over 60 peer reviewed publications. She edited and published a book entitled “Glycosaminoglycans in Development, Health, and Diseases with the contributions of top scientists worldwide in 2010 by Elsevier.
Mice deficient in heparan sulfate N-sulphotransferase-1
Lena Kjellén and Maria Ringvall
Mice deficient in heparan sulfate epimerase
Jin ping Li
Mice deficient in heparan sulfate 3-O-sulfotransferase-1 Nicholas W. Shworak
Mice deficient in heparan sulfate 6-O-sulfotransferase-1
Koji Kimata and Hiroko Habuchi
Mice deficient in dermatan sulfate Epimerase
Marco Maccarana and Anders Malmström
The roles of chondroitin-4-sulfotransferase-1 in development and disease
Michael Klüppel
Conditionally disrupted EXT1 in the embryonic mouse brain.
Yu Yamaguchi
Endothelial heparan sulfate in inflammation
Jeffrey D. Esko and Ding Xu
Endothelial heparan sulfate in angiogenesis
Jeffrey D. Esko, Mark M. Fuster and Lianchun Wang
Hepatocyte heparan sulfate and lipoprotein metabolism
Jeffrey D. Esko and Erin Foley
Serglycin proteoglycan deletion in mouse platelet
Barbara P. Schick
GAGs in Amyloidosis
Jin ping Li and Xiao Zhang
Selectins, Heparins and Tumor Metastasis
Lubor Borsig
Chondroitin sulfate and Rheumatoid arthritis
Lijuan Zhang
Adducted thumb-clubfoot syndrome (ACTS) and Loss of dermatan-4-sulfotransferase 1 function
Jacques U Baenziger,Thomas Müller, Andreas Janecke and Lijuan Zhang
Vascular dermatan sulfate and heparin cofactor II
Douglas M. Tollefsen
Diverse Functions of Glycosaminoglycans in Infectious Diseases
Pyong Woo Park, Rafael Aquino, and Eui Seung Lee
Lessons learned from contaminated heparin. 1: Molecular mechanism underlines heparin induced thrombocytopenia and thrombosis.
Lijuan Zhang
Lessons learne from contaminated heparin. 2: Contact System Activation-induced Thrombin in Unrelated Human Thromboembolic Diseases
Lijuan Zhang, Peter Weiser, Yi Qian and Jing Pan
| Reihe/Serie | Progress in Molecular Biology and Translational Science |
|---|---|
| Verlagsort | San Diego |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 960 g |
| Themenwelt | Medizin / Pharmazie |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 0-12-381282-8 / 0123812828 |
| ISBN-13 | 978-0-12-381282-7 / 9780123812827 |
| Zustand | Neuware |
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