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VEGF in Development

Christiana Ruhrberg (Herausgeber)

Buch | Hardcover
106 Seiten
2008
Springer-Verlag New York Inc.
978-0-387-78631-5 (ISBN)

Lese- und Medienproben

VEGF in Development -
CHF 149,75 inkl. MwSt
This book covers vascular endothelial growth factor A (VEGF or VEGFA), a secreted signaling protein. It highlights the central importance of this growth factor for vertebrate development.
his book is devoted to vascular endothelial growth factor A (VEGF his book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for or VEGFA), a secreted signalling protein of great significance for T development and disease in vertebrates. VEGFAcontrols the prolif- Tdevelopment and disease in vertebrates. VEGFA controls the prol- eration, eration, migration migration, , specialisatio specialisation n and and surviva survival l of vascula ofvascular r endothelia endothelial l cells, cells, and and iit t isis therefor therefore e essentia essential l for th for e establishmen the establishment t of a functiona ofa functional l blood vesse blood l vessel circuit. circuit. IIn n addition addition, , VEGF VEGFA A is emergin is emerging g as a versatil as a versatile e patternin patterning g factor fofactor r for several several non endothelia non-endothelial l celcell l type types s in vertebrates in vertebrates. .
ThusThus, , it playit s a centra plays al rol central e role during organ development at multiple levels, including blood vessel growth, duringorgan developmentat multiple levels, including blood vessel growth, vessel-mediated vessel mediated orga organ n inductio induction n andand tissutissue e differentiation differentiation. . The The discover discovery y ofof non endothelia non-endothelial l rolesroles for VEGF for VEGFA A initiallinitially y came ascarne a as a surprise. surprise.

The Biology of Vascular Endothelial Cell Growth Factor Isoforms.- VEGF Receptor Signalling in Vertebrate Development.- VEGF Gene Regulation.- Embryonic Vasculogenesis and Hematopoietic Specification.- Role of VEGF in Organogenesis.- VEGF and Endothelial Guidance in Angiogenic Sprouting.- Vascular and Nonvascular Roles of VEGF in Bone Development.- VEGF in the Nervous System.

Reihe/Serie Molecular Biology Intelligence Unit
Zusatzinfo 5 Illustrations, color; 10 Illustrations, black and white; XI, 106 p. 15 illus., 5 illus. in color.
Verlagsort New York, NY
Sprache englisch
Maße 165 x 248 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium 2. Studienabschnitt (Klinik) Pathologie
Naturwissenschaften Biologie Biochemie
ISBN-10 0-387-78631-7 / 0387786317
ISBN-13 978-0-387-78631-5 / 9780387786315
Zustand Neuware
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