VEGF in Development
Seiten
2010
|
Softcover reprint of hardcover 1st ed. 2008
Springer-Verlag New York Inc.
978-1-4419-2693-7 (ISBN)
Springer-Verlag New York Inc.
978-1-4419-2693-7 (ISBN)
This book covers vascular endothelial growth factor A (VEGF or VEGFA), a secreted signaling protein. It highlights the central importance of this growth factor for vertebrate development.
his book is devoted to vascular endothelial growth factor A (VEGF his book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for or VEGFA), a secreted signalling protein of great significance for T development and disease in vertebrates. VEGFAcontrols the prolif- Tdevelopment and disease in vertebrates. VEGFA controls the prol- eration, eration, migration migration, , specialisatio specialisation n and and surviva survival l of vascula ofvascular r endothelia endothelial l cells, cells, and and iit t isis therefor therefore e essentia essential l for th for e establishmen the establishment t of a functiona ofa functional l blood vesse blood l vessel circuit. circuit. IIn n addition addition, , VEGF VEGFA A is emergin is emerging g as a versatil as a versatile e patternin patterning g factor fofactor r for several several non endothelia non-endothelial l celcell l type types s in vertebrates in vertebrates. .
ThusThus, , it playit s a centra plays al rol central e role during organ development at multiple levels, including blood vessel growth, duringorgan developmentat multiple levels, including blood vessel growth, vessel-mediated vessel mediated orga organ n inductio induction n andand tissutissue e differentiation differentiation. . The The discover discovery y ofof non endothelia non-endothelial l rolesroles for VEGF for VEGFA A initiallinitially y came ascarne a as a surprise. surprise.
his book is devoted to vascular endothelial growth factor A (VEGF his book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for or VEGFA), a secreted signalling protein of great significance for T development and disease in vertebrates. VEGFAcontrols the prolif- Tdevelopment and disease in vertebrates. VEGFA controls the prol- eration, eration, migration migration, , specialisatio specialisation n and and surviva survival l of vascula ofvascular r endothelia endothelial l cells, cells, and and iit t isis therefor therefore e essentia essential l for th for e establishmen the establishment t of a functiona ofa functional l blood vesse blood l vessel circuit. circuit. IIn n addition addition, , VEGF VEGFA A is emergin is emerging g as a versatil as a versatile e patternin patterning g factor fofactor r for several several non endothelia non-endothelial l celcell l type types s in vertebrates in vertebrates. .
ThusThus, , it playit s a centra plays al rol central e role during organ development at multiple levels, including blood vessel growth, duringorgan developmentat multiple levels, including blood vessel growth, vessel-mediated vessel mediated orga organ n inductio induction n andand tissutissue e differentiation differentiation. . The The discover discovery y ofof non endothelia non-endothelial l rolesroles for VEGF for VEGFA A initiallinitially y came ascarne a as a surprise. surprise.
The Biology of Vascular Endothelial Cell Growth Factor Isoforms.- VEGF Receptor Signalling in Vertebrate Development.- VEGF Gene Regulation.- Embryonic Vasculogenesis and Hematopoietic Specification.- Role of VEGF in Organogenesis.- VEGF and Endothelial Guidance in Angiogenic Sprouting.- Vascular and Nonvascular Roles of VEGF in Bone Development.- VEGF in the Nervous System.
| Erscheint lt. Verlag | 19.11.2010 |
|---|---|
| Reihe/Serie | Molecular Biology Intelligence Unit |
| Zusatzinfo | 5 Illustrations, color; 10 Illustrations, black and white; XI, 106 p. 15 illus., 5 illus. in color. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 165 x 248 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Studium ► 2. Studienabschnitt (Klinik) ► Pathologie | |
| Naturwissenschaften ► Biologie ► Biochemie | |
| ISBN-10 | 1-4419-2693-3 / 1441926933 |
| ISBN-13 | 978-1-4419-2693-7 / 9781441926937 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
Mehr entdecken
aus dem Bereich
aus dem Bereich
Klinisch-pathologische Übersichtskarten
Buch | Hardcover (2023)
Springer (Verlag)
CHF 48,95
