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Legionella Pneumophila: Pathogenesis and Immunity

Paul Hoffman, Herman Friedman, Mauro Bendinelli (Herausgeber)

Buch | Hardcover

208 Seiten

2007
Springer-Verlag New York Inc.
978-0-387-70895-9 (ISBN)

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Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. There have been new developments in this field including the publication of three whole genome sequences, the discovery of a developmental cycle and novel cyst-like highly infectious form, and the bacteria have been used as a probe for macrophage cellular function to unravel fundamental new knowledge in the area of cellular biology. Legionella has also become a model system for the study of innate as well as adaptive immunity. Information on Legionella continues to increase in the U.S. and abroad. Columbia University has started the first Legionella Genome Project with a multi-million dollar grant from the NIH. In addition, The European Working Group for Legionella infections was formed in 1986. Members are scientists with an interest in improving knowledge and information on the clinical and environmental aspects of legionnaires' disease through developments in diagnosis, management and treatment of the disease. The volume brings together all of the lastest research on this pathogen, the interest in which is rapidly growing.

Legionella pneumophila Pathogenesis: Lessons Learned from Genomics.- Iron Assimilation and Type II Protein Secretion.- The Dot/Icm Type IVB Secretion System.- Life Cycle, Growth Cycles and Developmental Cycle of Legionella pneumophila.- Legionella in the Environment.- Regulation of the Legionella pneumophila Life Cycle.- Microbial Physiology.- Legionnaires’ Disease—Clinical Picture.- Legionella pneumophila:Innate and Adaptive Immunity.- Nonspecific Stimulation of Immunity Against Legionella.- Interaction of Legionella pneumophila with Amoeba.

Reihe/Serie	Infectious Agents and Pathogenesis
Zusatzinfo	XVIII, 208 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	156 x 235 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Pneumologie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
ISBN-10	0-387-70895-2 / 0387708952
ISBN-13	978-0-387-70895-9 / 9780387708959
Zustand	Neuware