Handbook of Drug Metabolism

Buch | Softcover

612 Seiten

2019
CRC Press (Verlag)
978-0-367-39985-6 (ISBN)

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Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.

Thomas F. Woolf

Fundamental Aspects of Drug Metabolism. Factors Affecting Drug Metabolism. Technologies. Metabolism in Drug Discovery and Development.

Erscheinungsdatum	18.09.2019
Verlagsort	London
Sprache	englisch
Maße	178 x 254 mm
Gewicht	453 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-367-39985-7 / 0367399857
ISBN-13	978-0-367-39985-6 / 9780367399856
Zustand	Neuware