Handbook of Drug Metabolism
Seiten
1999
Crc Press Inc (Verlag)
978-0-8247-0229-8 (ISBN)
Crc Press Inc (Verlag)
978-0-8247-0229-8 (ISBN)
Provides a framework for drug metabolism in drug discovery and development. Bringing together collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. It contains tables, drawings, photographs, and equations.
Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.
Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.
Thomas F. Woolf
Fundamental Aspects of Drug Metabolism. Factors Affecting Drug Metabolism. Technologies. Metabolism in Drug Discovery and Development.
Erscheint lt. Verlag | 29.3.1999 |
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Verlagsort | Bosa Roca |
Sprache | englisch |
Maße | 178 x 254 mm |
Gewicht | 1290 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
Naturwissenschaften ► Biologie ► Biochemie | |
Technik | |
ISBN-10 | 0-8247-0229-8 / 0824702298 |
ISBN-13 | 978-0-8247-0229-8 / 9780824702298 |
Zustand | Neuware |
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