Stroke Genetics

Pankaj Sharma, James F. Meschia (Herausgeber)

Buch | Softcover

XII, 431 Seiten

2018 | 2nd ed. 2017
Springer International Publishing (Verlag)
978-3-319-85854-8 (ISBN)

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This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.

Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

Pankaj Sharma, MD, PhD, FRCP Reader & Consultant Neurologist Imperial College London & Hammersmith Hospitals London, UK James F. Meschia, MD Chair, Department of Neurology Mayo Clinic Jacksonville, Florida, USA

Introduction.- Familial stroke epidemiology.- Association study results.- GWAS.- Aneurysms/carvernous/AVM.- ICH/amyloid/microbleeds.- CADASIL.- Fabry.- MELAS.- Sickle.- Other monogenic.- White matter disease.- Carotid atherosclerosis.- Dissection.- Pharmacogenomics.- Non-Caucasian stroke genetics.- Small vessel disease.- Genetics of neuroimaging in stroke.- Cerebrovenous thrombosis.- Ethics.

Erscheint lt. Verlag	12.8.2018
Zusatzinfo	XII, 431 p. 39 illus., 26 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	908 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
Schlagworte	CADASIL • Cerebral hemorrhage • Fabry • Genetics • Genome • GWAS • Hypertension • MELAS • Stem Cell • stroke
ISBN-10	3-319-85854-8 / 3319858548
ISBN-13	978-3-319-85854-8 / 9783319858548
Zustand	Neuware