Stroke Genetics

Pankaj Sharma, James F. Meschia (Herausgeber)

Buch | Hardcover

XII, 431 Seiten

2017 | 2nd ed. 2017
Springer International Publishing (Verlag)
978-3-319-56208-7 (ISBN)

Infos

This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.

Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

Autor

Pankaj Sharma, MD, PhD, FRCPReader & Consultant NeurologistImperial College London & Hammersmith HospitalsLondon, UKJames F. Meschia, MDChair, Department of NeurologyMayo ClinicJacksonville, Florida, USA

Inhalt

Introduction.- Familial stroke epidemiology.- Association study results.- GWAS.- Aneurysms/carvernous/AVM.- ICH/amyloid/microbleeds.- CADASIL.- Fabry.- MELAS.- Sickle.- Other monogenic.- White matter disease.- Carotid atherosclerosis.- Dissection.- Pharmacogenomics.- Non-Caucasian stroke genetics.- Small vessel disease.- Genetics of neuroimaging in stroke.- Cerebrovenous thrombosis.- Ethics.

Produkt-Details

• Erscheinungsdatum: 06.07.2017
• Zusatzinfo: XII, 431 p. 39 illus., 26 illus. in color.
• Verlagsort: Cham
• Sprache: englisch
• Maße: 155 x 235 mm
• Gewicht: 882 g
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
• Schlagworte: CADASIL • Cerebral hemorrhage • Clinical & internal medicine • Clinical & internal medicine • Fabry • Genetics • Genome • GWAS • Human genetics • Hypertension • Internal Medicine • medical genetics • Medicine • Medicine: general issues • MELAS • Neurology • Neurology & clinical neurophysiology • Neurology & clinical neurophysiology • Schlaganfall • Stem Cell • stroke
• ISBN-10: 3-319-56208-8 / 3319562088
• ISBN-13: 978-3-319-56208-7 / 9783319562087
• Zustand: Neuware