Multiscale Mechanobiology of Bone Remodeling and Adaptation

Buch | Softcover

XII, 287 Seiten

2018 | 1. Softcover reprint of the original 1st ed. 2018
Springer International Publishing (Verlag)
978-3-319-86489-1 (ISBN)

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The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors.
Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.

Bone cell biology and mechanobiology.- Disease systems analysis of osteoporosis and treatments.- Bone quality assessment across the scales.- Interaction of bone tissue with other tissues including muscle, cartilage, and vascularization.- Musculoskeletal modeling of human movement.- Image-based 3D micro-FE modeling.

Erscheinungsdatum	02.10.2018
Reihe/Serie	CISM International Centre for Mechanical Sciences
Zusatzinfo	XII, 287 p. 98 illus.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	462 g
Themenwelt	Medizinische Fachgebiete ► Chirurgie ► Unfallchirurgie / Orthopädie
	Technik ► Maschinenbau
	Technik ► Umwelttechnik / Biotechnologie
Schlagworte	bone remodeling • Disease Systems Analysis • Mechanobiology • Multiscale Computational Modeling • Musculoskeletal Modeling
ISBN-10	3-319-86489-0 / 3319864890
ISBN-13	978-3-319-86489-1 / 9783319864891
Zustand	Neuware