Multiscale Mechanobiology of Bone Remodeling and Adaptation

Buch | Hardcover

XII, 287 Seiten

2017 | 1st ed. 2018
Springer International Publishing (Verlag)
978-3-319-58843-8 (ISBN)

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The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors.
Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.

Bone cell biology and mechanobiology.- Disease systems analysis of osteoporosis and treatments.- Bone quality assessment across the scales.- Interaction of bone tissue with other tissues including muscle, cartilage, and vascularization.- Musculoskeletal modeling of human movement.- Image-based 3D micro-FE modeling.

Erscheinungsdatum	13.07.2017
Reihe/Serie	CISM International Centre for Mechanical Sciences
Zusatzinfo	XII, 287 p. 98 illus.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	613 g
Themenwelt	Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik
	Medizinische Fachgebiete ► Chirurgie ► Unfallchirurgie / Orthopädie
	Technik ► Maschinenbau
	Technik ► Umwelttechnik / Biotechnologie
Schlagworte	biomaterials • Biotechnology • bone remodeling • Continuum Mechanics and Mechanics of Materials • Disease Systems Analysis • Engineering • Engineering: general • Materials Science • mechanical engineering & materials • Mechanical engineering & materials • Mechanobiology • Multiscale Computational Modeling • Musculoskeletal Modeling • Orthopedics • surgical orthopaedics & fractures • Surgical orthopaedics & fractures
ISBN-10	3-319-58843-5 / 3319588435
ISBN-13	978-3-319-58843-8 / 9783319588438
Zustand	Neuware