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Mechanosensory Transduction in Drosophila Melanogaster - Xin Liang, Landi Sun, Zhen Liu

Mechanosensory Transduction in Drosophila Melanogaster (eBook)

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2017 | 1st ed. 2017
IX, 82 Seiten
Springer Singapore (Verlag)
978-981-10-6526-2 (ISBN)
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This book offers an essential introduction for all graduate students and researchers who are working on or interested in mechanotransduction using fruit flies as their model organisms. Designed for accessibility, it follows a simple five-chapter structure, beginning with a general introduction to mechanotransduction in physiology (Chapter 1) and some basic considerations on the principles behind mechanotransduction processes (Chapter 2). In turn, Chapters 3, 4 and 5 focus on mechanoreceptors in Drosophila melanogaster. Chapter 3 explains how the fly's mechanosensitive cells (i.e. mechanoreceptors) contribute to its daily life, while Chapter 4 explores the ultrastructural and mechanical basis for the working mechanisms of various fly mechanoreceptors. Lastly, Chapter 5 elaborates on the structure, function and physiology of mechanosensitive molecules in fly mechanoreceptors.

Accordingly, the book provides an overall framework, helping readers understand

mechanosensory transduction, from the physiological level to the molecular level.



Xin Liang is a biophysicist. He received his B.S. degree and Ph.D. from Shanghai Jiao Tong University in 2003 and 2007, respectively. He then moved to the Max-Planck Institute for Molecular Cell Biology and Genetics in Dresden, Germany for postdoctoral research (Supervisor: Prof. Jonathon Howard). In 2015, he moved back to China and started his own research group at the School of Life Sciences, Tsinghua University in Beijing. Currently, his primary research interest is in understanding 'how cells sense forces' at both the cell biological and molecular level.  

Landi Sun received her Ph.D. from Lanzhou University in 2015. Soon after, she began her postdoctoral research at Tsinghua University. She is currently investigating the structural-mechanical basis of mechanotransduction in Drosophila melanogaster.

Zhen Liu graduated from Tsinghua University in 2015 (B.S.), where he is now a graduate student. His current focus is on understanding how diffe

rent mechanoreceptors differentiate between different mechanical stimuli.


This book offers an essential introduction for all graduate students and researchers who are working on or interested in mechanotransduction using fruit flies as their model organisms. Designed for accessibility, it follows a simple five-chapter structure, beginning with a general introduction to mechanotransduction in physiology (Chapter 1) and some basic considerations on the principles behind mechanotransduction processes (Chapter 2). In turn, Chapters 3, 4 and 5 focus on mechanoreceptors in Drosophila melanogaster. Chapter 3 explains how the fly's mechanosensitive cells (i.e. mechanoreceptors) contribute to its daily life, while Chapter 4 explores the ultrastructural and mechanical basis for the working mechanisms of various fly mechanoreceptors. Lastly, Chapter 5 elaborates on the structure, function and physiology of mechanosensitive molecules in fly mechanoreceptors. Accordingly, the book provides an overall framework, helping readers understand mechanosensory transduction, from the physiological level to the molecular level.

Xin Liang is a biophysicist. He received his B.S. degree and Ph.D. from Shanghai Jiao Tong University in 2003 and 2007, respectively. He then moved to the Max-Planck Institute for Molecular Cell Biology and Genetics in Dresden, Germany for postdoctoral research (Supervisor: Prof. Jonathon Howard). In 2015, he moved back to China and started his own research group at the School of Life Sciences, Tsinghua University in Beijing. Currently, his primary research interest is in understanding “how cells sense forces” at both the cell biological and molecular level.  Landi Sun received her Ph.D. from Lanzhou University in 2015. Soon after, she began her postdoctoral research at Tsinghua University. She is currently investigating the structural-mechanical basis of mechanotransduction in Drosophila melanogaster. Zhen Liu graduated from Tsinghua University in 2015 (B.S.), where he is now a graduate student. His current focus is on understanding how different mechanoreceptors differentiate between different mechanical stimuli.

Overview of Mechanosensory Transduction.- “Gating-Spring” Model for Mechanotransduction.- Mechanoreceptors in Drosophila melanogaster.- Mechanotransduction in Drosophila mechanoreceptors.- Drosophila Mechanotransduction Channels.

Erscheint lt. Verlag 11.10.2017
Reihe/Serie SpringerBriefs in Biochemistry and Molecular Biology
SpringerBriefs in Biochemistry and Molecular Biology
Zusatzinfo IX, 82 p. 30 illus., 26 illus. in color.
Verlagsort Singapore
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Medizin / Pharmazie Studium
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
Schlagworte Drosophila melanogaster • Gating-Spring Model • mechanoreceptor • Mechanosensitive channel • Mechanosensory transduction
ISBN-10 981-10-6526-8 / 9811065268
ISBN-13 978-981-10-6526-2 / 9789811065262
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