New Research on Dihydropyridines

Buch | Softcover

2016
Nova Science Publishers Inc (Verlag)
978-1-63485-604-1 (ISBN)

Artikel merken

Dihydropyridines (DHPs) are one of the most important nitrogen-containing heterocycles which are widely recognized in the scaffold of various biologically active compounds and natural products. DHPs are also utilized as medicines and useful building blocks for the complex molecules. On the other hand, some DHPs exhibit blue fluorescence in organic solvents and have potential to apply as functional materials. Based on the novel utility of DHPs in both medicinal chemistry and material sciences, development of efficient and robust synthetic methods for DHPs has been paid much attention and a large number of synthesis of DHPs have been reported. The first chapter in this book summarizes recent progress in synthetic methodologies for the construction of DHP scaffolds both in catalytic and in stoichiometric manners (particularly from 2000 to present), which are classified by the reaction patterns as 1) Multi-Component Coupling Reactions, 2) Pericyclic Reactions, 3) Regioselective Transformation of Pyridines, and 4) Miscellaneous. Chapter Two focuses on the synthesis of 1,4-DHPs and derivative compounds by using different routes of synthesis and greener alternatives. Chapter Three describes a mild and efficient protocol for the synthesis of 1,4-dihydropyridines via four component reactions of aromatic aldehydes, dimedone, ethyl acetoacetate or methyl acetoacetate and ammonium acetate using Fe(ClO4)3/SiO2. Chapter Four reviews the synthesis of chiral dihydropyridines.

For Complete Table of Contents, please visit our website at: https://www.novapublishers.com/catalog/product_info.php?products_id=59039

Erscheinungsdatum	07.09.2016
Zusatzinfo	Illustrations
Verlagsort	New York
Sprache	englisch
Maße	155 x 230 mm
Gewicht	340 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Chemie
ISBN-10	1-63485-604-X / 163485604X
ISBN-13	978-1-63485-604-1 / 9781634856041
Zustand	Neuware