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The Benzodiazepine Receptor

Drug Acceptor Only or a Physiologically Relevant Part of our Central Nervous System?
Buch | Hardcover
200 Seiten
1987
Cambridge University Press (Verlag)
978-0-521-30418-4 (ISBN)
CHF 74,20 inkl. MwSt
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Benzodiazepines are the most commonly used psychotropic drugs, prescribed for their action as tranquillizers, hypnotics and anti-epileptics. They act in the brain by binding to specific, highly selective recognition sites, the benzodiazepine receptors. This book, first published in 1987, summarises our knowledge of these receptors for a student and professional audience.
Benzodiazepines are the most commonly used psychotropic drugs, prescribed for their action as tranquillizers, hypnotics and anti-epileptics. They act in the brain by binding to specific, highly selective recognition sites, the benzodiazepine receptors. This book, first published in 1987, summarises our knowledge of these receptors for a student and professional audience and is divided into two sections. In the first part, the general properties of the receptors and their involvement in the mechanisms of action of benzodiazepines are described. The second part discusses the function of the receptors and concludes that the system represents a novel neuronal system for the fine adjustment of brain function or for auxiliary function if the other neuronal systems fail owing to pathological defects.

Preface; 1. Introduction; 2. General aspects of the benzodiazepine receptor; 3. The benzodiazepine receptor as the primary target of benzodiazepine drugs in the brain; 4. The benzodiazepine receptor as a modulatory unit of GABAergic neurotransmission; 5. The benzodiazepine receptor in human brain; 6. Is there a physiological function?; 7. Pathological changes in the benzodiazepine receptor in animals and man; 8. Drug acceptor or physiological receptor?; 9. Future aspects for therapy and research in psychiatry; Appendix 1. The benzodiazepine radioreceptor assay: a rapid and sensitive method to detect benzodiazepines in biological tissues; Appendix 2. Abbreviations; References; Index.

Erscheint lt. Verlag 10.12.1987
Reihe/Serie The Scientific Basis of Psychiatry
Verlagsort Cambridge
Sprache englisch
Maße 152 x 228 mm
Gewicht 412 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Psychiatrie / Psychotherapie
ISBN-10 0-521-30418-0 / 0521304180
ISBN-13 978-0-521-30418-4 / 9780521304184
Zustand Neuware
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