Research Surgery and Care of the Research Animal (eBook)

Surgical Approaches to the Organ Systems

William I. Gay, James E. Heavner (Herausgeber)

eBook Download: PDF

2013 | 1. Auflage
250 Seiten
Elsevier Science (Verlag)
978-1-4832-5972-7 (ISBN)

Infos

Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part C is a collection of papers that deals with methods used in animal experiments concerning surgical approaches to certain organ systems such as the maxillofacial and skin systems. This collection deals with surgery involving the oral and maxillofacial, ophthalmic, skin systems, as well as research on canine immune systems and applications of microsurgery and laser surgery. One paper discusses orthognathic surgery including temporomandibular joint and dental implants. Another paper describes corneal procedures, lens extraction, and intraocular lenses. In discussing skin experimental surgery, the author explains procedures in flap anatomy, surgical healing, skin grafting, and burn treatment. The techniques in studying the immune systems of dogs include procedures dealing with peripheral blood, bone marrow, reactive cells, and tissues. Other authors explain the application of microsurgery to laboratory research including the equipment and techniques used, as well as the general principles of tissue transplantation into the animal's central nervous system. Another author discusses the use of lasers and special considerations such as laser restrictions and instrumentation. This book will be appreciated by laboratory assistants and scientists dealing with test animals, by veterinarians, and by researchers designing animal and medical experiments.

Inhalt

Front Cover 1
Research Surgery and Care of the Research Animal: Surgical Approaches to the Organ Systems 4
Copyright Page 5
Table of Contents 6
FOREWORD 10
PREFACE 12
Chapter 1. Animal Research Models in Oral and Maxillofacial Surgery 14
I. Introduction 14
II. Orthognathic Surgery 15
III. Experimental Fractures 23
IV. Temporomandibular Joint 25
V. Bone Grafting 33
VI. Dental Implants 37
VII. Osteomyelitis 40
VIII. Tooth Transplantation 40
IX. Alveolar Cleft Grafts 42
X. Summary 42
References 44
Chapter 2. Ophthalmic Surgery on Laboratory Animals 48
I. Introduction 48
II. Corneal Procedures 50
III. Lens Extraction and Intraocular Lenses 60
IV. Intraocular Injections 65
V. Vitrectomy 68
VI. Use of Surgical Models in Glaucoma Research 70
VII. Lasers in Ophthalmic Surgery 76
VIII. Adjunctive Medications and Devices in Intraocular Surgery 81
References 85
Chapter 3. Experimental Skin Surgery 88
I. Introduction 88
II. Flap Anatomy and Physiology 90
III. Microsurgery 99
IV. Wound Healing as It Relates to Skin Surgery 106
V. Skin Grafting 108
VI. Burns 111
VII. Summary 113
References 113
Chapter 4. Experimental Techniques Used to Study the Immune System of Dogs and Other Large Animals 116
I. Introduction 117
II. Immunologically Reactive Tissue 117
III. Immunocompetence and Immunosuppression 120
IV. Experimental Techniques for Peripheral Blood 129
V. Experimental Techniques for Bone Marrow 131
VI. Procedures Involving Other Immunologically Reactive Cells and Tissues 136
VII. Procedures for Establishing and Using Experimental Immune Models.. 140
References 143
Chapter 5. The Application of Microsurgery to Laboratory Research 148
I. Introduction and History 148
II. Equipment 149
III. Techniques 167
IV. Summary and Future Laboratory Microsurgery 180
References 182
Chapter 6. Neurotransplantation 184
I. History and Rationale 184
II. General Principles of Transplantation into the Nervous System 185
III. Model Systems for Transplantation 200
IV. Immunology of CNS Transplants 211
V. Vascularity of Neural Transplants 214
VI. Conclusions 215
References 216
Chapter 7. Experimental Surgery Using Lasers 220
I. Introduction 220
II. Laser Physics 221
III. Special Considerations 225
IV. Laser–Tissue Interactions 232
V. Animal Models for Surgical Applications of Lasers 237
References 242
INDEX 244

Produkt-Details

• Erscheint lt. Verlag: 22.10.2013
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Laboratoriumsmedizin
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Technik
• ISBN-10: 1-4832-5972-2 / 1483259722
• ISBN-13: 978-1-4832-5972-7 / 9781483259727