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Research Surgery and Care of the Research Animal -

Research Surgery and Care of the Research Animal (eBook)

Surgical Approaches to the Organ Systems
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2013 | 1. Auflage
280 Seiten
Elsevier Science (Verlag)
978-1-4832-5954-3 (ISBN)
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Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part B is a collection of papers that deals with methods used in animal experiments concerning surgical approaches to certain organ systems. This collection deals with surgery involving the respiratory, cardiovascular, skeletal, gastrointestinal, genital, and central nervous systems of the test animals. One paper describes the procedures to be followed in thoracic incisions, emphasizing the importance of access to airways and parenchymal resections. In explaining cardiovascular surgery, one paper details the specialized surgical equipment, anesthesia, blood flow, and post-operative care that the test animal needs. Another paper describes the procedures and techniques, as well as limb immobilization or total joint prostheses that should be followed in a surgery involving the skeletal system. One author also considers in detail both research surgeries of the male and female reproductive tracts. The paper on surgery involving the peripheral and central nervous system gives general techniques used in chronic studies of such system. Veterinarians, laboratory workers dealing with test animals, and researchers designing animal and medical experiments will find this book very informative.
Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part B is a collection of papers that deals with methods used in animal experiments concerning surgical approaches to certain organ systems. This collection deals with surgery involving the respiratory, cardiovascular, skeletal, gastrointestinal, genital, and central nervous systems of the test animals. One paper describes the procedures to be followed in thoracic incisions, emphasizing the importance of access to airways and parenchymal resections. In explaining cardiovascular surgery, one paper details the specialized surgical equipment, anesthesia, blood flow, and post-operative care that the test animal needs. Another paper describes the procedures and techniques, as well as limb immobilization or total joint prostheses that should be followed in a surgery involving the skeletal system. One author also considers in detail both research surgeries of the male and female reproductive tracts. The paper on surgery involving the peripheral and central nervous system gives general techniques used in chronic studies of such system. Veterinarians, laboratory workers dealing with test animals, and researchers designing animal and medical experiments will find this book very informative.

Front Cover 1
Research Surgery and Care of the Research Animal, Part B 4
Copyright Page 5
Table of Contents 
6 
Foreword 8
Preface 10
Chapter 1. Surgery of the Respiratory System 12
I. Introduction 12
II. Thoracic Incisions for Model Preparations 14
III. Access to Airways and Parenchymal Resections 19
IV. Models for Measurement of Lung Fluid and Protein Flux 22
ACKNOWLEDGMENT 40
References 40
Chapter 2. Cardiovascular Surgery for Chronic Experimentation in Conscious Animals 42
I. Introduction 42
II. Hemodynamic Measurements 43
III. Surgical Equipment and Instruments 49
IV. Preoperative Care 50
V. Anesthesia 51
VI. Thoracic Surgery 52
VII. Instrumentation of the Thoracic Cavity 57
VIII. Dimensions 60
IX. Blood Flow 62
X. Abdominal Surgery 64
XI. Surgical Techniques to Interrupt the Neural Control of the Cardiovascular System 66
XII. Vascular Surgery 71
XIII. Postoperative Care 72
References 74
Chapter 3. Experimental Surgery of the Skeletal System 78
I. Introduction 78
II. Special Considerations in Species Selection 79
III. Procedures and Techniques 84
IV. General Postoperative Considerations 99
V. Limb Immobilization: External Coaptation 99
VI. Specific Animal Models 100
VII. Total Joint Prostheses 111
References 111
Chapter 4. The Gastrointestinal Tract 120
I. Introduction 120
II. Cannulas Used for Chronic Preparations 121
III. Esophageal Preparations 125
IV. Surgical Preparations for the Study of Gastric Function 129
V. Preparations for the Study of Pancreatic Function 149
VI. Preparations for the Study of Biliary Function 158
VII. Intestinal Preparations 160
VIII. Miscellaneous 162
References 165
Chapter 5. Experimental Surgery of the Genital System 168
I. Introduction 168
II. Selection of Animal Models 170
III. Technical Considerations in Genital Surgery 173
IV. Research Surgery of the Male Reproductive Tract 176
V. Research Surgery of the Female Reproductive Tract 199
References 221
Chapter 6. Peripheral and Central Nervous System 228
I. Introduction 228
II. Peripheral Nervous System 229
III. Central Nervous System 253
References 267
INDEX 270

Erscheint lt. Verlag 3.9.2013
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Laboratoriumsmedizin
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie
Technik
ISBN-10 1-4832-5954-4 / 1483259544
ISBN-13 978-1-4832-5954-3 / 9781483259543
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