Research Surgery and Care of the Research Animal (eBook)

Patient Care, Vascular Access, and Telemetry

William I. Gay, James E. Heavner (Herausgeber)

eBook Download: PDF

2013 | 1. Auflage
266 Seiten
Elsevier Science (Verlag)
978-1-4832-5953-6 (ISBN)

Infos

Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part A is a collection of papers that deals with methods used in animal experiments involving patient care, vascular access, and telemetry. This book concerns technologies in experimental surgery - complicated procedures requiring longer observation time of the test animal, and an increase in the spectrum of animals that can be used. One paper describes the anesthesia, analgesia, and kinds of restraints that are suited for the test animal. A wide array of choices of inhalational agents, injectable, local anesthesia (lidocaine), analgesics (opioids and aspirin), and restraint (nonanesthesia and neuromuscular-blocking agents) is available for the researcher to choose from. Several authors also describe the use of telemetry devices that are implantable in test animals to achieve minimal interference from the investigator. These devices include sensors such as flow transducers and probes to use in pulse or continuous wave-applications; electromagnetic flowmeters for blood monitoring; and integrated circuits for various applications. One paper discusses postoperative care including a patient care checklist, treatment of common postoperative complications, as well as venous catheters for fluid administration. This text will be appreciated by veterinarians, technicians dealing with laboratory animals, and researchers designing animal and medical experiments.

Inhalt

Front Cover 1
Research Surgery and Care of the Research Animal: Patient Care, Vascular Access, and Telemetry 4
Copyright Page 5
Table of Contents 6
FOREWORD 8
PREFACE 10
Chapter 1. Anesthesia, Analgesia, and Restraint 12
I. Introduction 12
II. General Anesthesia: Inhalation Agents 13
III. General Anesthesia: Agents Given by Other Than the Inhalational Route 22
IV. Local Anesthesia 26
V. Analgesia 27
VI. Restraint 29
VII. Application Notes 31
VIII. Concluding Comments 43
Appendix I: Sources of Equipment, Supplies, and Drugs 43
Appendix II: Drug Schedules per Controlled Substance Act of 1970 (U.S.A.) 44
References 45
Chapter 2. Implantable Telemetry 48
I. Introduction 48
II. Applications 50
III. Sensors 69
IV. Systems 85
V. Integrated Circuits 101
VI. Implant Technology 110
VII. External Electronics Used with Implantable Telemetry 114
References 118
Chapter 3. Postoperative Care 124
I. Introduction 124
II. Postoperative Patient Care Checklist 125
III. Causes and Treatments of Common Postoperative Complications 127
IV. Introduction and Maintenance of Indwelling Venous Catheters for Fluid Administration 148
References 151
Chapter 4. Indwelling Vascular Cannulas for Remote Blood Sampling, Infusion, and Long-Term Instrumentation of Small Laboratory Animals 154
I. Introduction 154
II. Selection of Materials for Intravascular Catheters 155
III. Design of Experiments Requiring Blood Sampling and Intravascular Access 166
IV. Physiological Constraints Imposed by Small Body Mass 173
V. Blood Sampling and Injection of Animals without Cannulas 176
VI. Surgical Techniques for Intravascular Cannulation 177
VII. Blood Sampling and Infusion from Intravascular Cannulas 188
VIII. Remote Access Intravascular Cannulas 189
IX. Implantable Infusion Pumps 198
X. Overview and Conclusions 199
References 200
Chapter 5. Vascular Access in Large Laboratory Animals 206
I. Introduction 206
II. General Considerations 208
III. Methods of Blood Access 225
IV. Factors Influencing Animal Selection 249
V. Conclusion 249
References 250
INDEX 254

Produkt-Details

• Erscheint lt. Verlag: 22.10.2013
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Laboratoriumsmedizin
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Technik
• ISBN-10: 1-4832-5953-6 / 1483259536
• ISBN-13: 978-1-4832-5953-6 / 9781483259536