The Bone Biopsy

Buch | Softcover

158 Seiten

2012 | Softcover reprint of the original 1st ed. 1977
Springer-Verlag New York Inc.
978-1-4684-2381-5 (ISBN)

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During the last ten years, the diagnostic approach to disorders of bone and mineral metabolism has benefited considerably from the development of radioimmunoassay and competitive protein- binding techniques for measurements of circulating parathyroid hormone, calcitonin, and biologically active vitamin D me- tabolites. Accumulated experiences with radiogrametrical and densinometric methods of quantitating appendicular bone mass now facilitate the detection of changes in bone mineral content heretofore unrecognized by routine roentgenographic vertebral analysis. During this same decade, the diagnosis of metabolic bone disease and the skeletal response to remedial therapeutic ma- neuvers have also been facilitated by the routine application of the bone biopsy. Improvements in tinctorial techniques, stan- dardization in methodology essential for adequate preparation of thin undecalcified specimens, and the incorporation of tetracy- cline bone formation or mineralization "markers" should now herald the "routine" use of this diagnostic procedure.
Moreover, the compilation and ready availability of reference morphometric data, spanning the prepubescent years charac- terized by skeletal growth and remodeling and the later senes- cent period during which bone loss normally proceeds in an un- 7 8 FOREWORD relenting fashion, allow adequate differentiation between normal age-sex-related changes in skeletal turnover attendant on skeletal maturation and aging and acquired or inherited de- rangements in bone metabolism.

1 • Bone Structure.- 2 • Cell Origins.- 3 • Cortical and Trabecular Bone.- 4 • The Bone Biopsy.- 5 • Methods of Analysis.- 6 • Identification of Bone Cell Activity.- 7 • Bone Biopsy Results in Pathological Conditions.- 8 • Conclusions.- References.

Erscheint lt. Verlag	8.7.2012
Reihe/Serie	Topics in bone and mineral disorders
Zusatzinfo	57 Illustrations, black and white; 158 p. 57 illus.
Verlagsort	New York, NY
Sprache	englisch
Themenwelt	Sachbuch/Ratgeber ► Natur / Technik ► Garten
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Diabetologie
ISBN-10	1-4684-2381-9 / 1468423819
ISBN-13	978-1-4684-2381-5 / 9781468423815
Zustand	Neuware