GPCR Molecular Pharmacology and Drug Targeting (eBook)

Shifting Paradigms and New Directions

Annette Gilchrist (Herausgeber)

eBook Download: PDF

2010 | 1. Auflage
544 Seiten
John Wiley & Sons (Verlag)
978-0-470-62731-0 (ISBN)

Infos

G protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms in G Protein Coupled Receptors takes a look at the way GPCRs are examined today, how they react, how their mutations lead to disease, and the many ways in which they can be screened for compounds that modulate them. Chemists, pharmacologists, and biologists will find essential information in this comprehensive reference.

Autor

Annette Gilchrist, PhD, is Assistant Professor of Pharmaceutical Sciences at Midwestern Univeristy's Chicago of Pharmacy, and Adjunct Professor at Northwestern University in the Department of Molecular Pharmacology and Biological Chemistry. Previously, she cofounded and was chief scientific officer for Caden Biosciences, and cofounded and was president of Cue BIOtech, companies committed to GPCR discovery efforts. A life sciences industry consultant and regular speaker at ACS, SBS, DIA, BIO, and CHI conferences, she has twenty-four peer-reviewed publications and four issued patents.

Rezensionen

"Additionally, the presentation of the fundamental concepts of GPCR biology by the authors, who are recognized experts in the GPCR field, is likely to be appreciated by students of pharmacology. . . This is a unique resource for navigating the field of GPCR research." (Doody's, 23 September 2011)

". . . scientists whose area of research is (or will be) connected with GPCRs ... will get a comprehensive overview of current state-of-the-art research in this broad and rapidly developing field." (ChemMedChem, 1 February 2011)

Produkt-Details

• Erscheint lt. Verlag: 8.6.2010
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Chemie
• Schlagworte: Biowissenschaften • Chemie • Chemistry • Drug Discovery & Development • Life Sciences • Medical Science • Medizin • Pharmacology & Pharmaceutical Medicine • Pharmakologie • Pharmakologie u. Pharmazeutische Medizin • Proteine u. Makromoleküle • Proteine u. Makromoleküle • Proteins & Macromolecules • Wirkstoffforschung u. -entwicklung
• ISBN-10: 0-470-62731-X / 047062731X
• ISBN-13: 978-0-470-62731-0 / 9780470627310