Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine (eBook)

Sheng Ding (Herausgeber)

eBook Download: PDF

2008 | 1. Auflage
272 Seiten
John Wiley & Sons (Verlag)
978-0-470-19912-1 (ISBN)

Infos

Promising technologies for exploring stem cells

Scientists believe that stem cells have the potential to repair specific tissues and to grow organs, revolutionizing the treatment of cardiovascular disease, neurodegenerative disease, musculoskeletal disease, diabetes, and cancer. A core reference for researchers, Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine consolidates the latest information on functional genomics and chemical biology approaches that are used to study and control the fate of stem cells. It discusses new technologies and their recent applications in various areas of stem cell biology, covering:

* The use of both embryonic and adult stem cells

* A vast array of technologies, including: genome-wide expression analysis, functional genomic profiling with arrayed cDNA and RNAi expression libraries, informatics, chemical genomics, mass spectrometry, and proteomics

* The applications of advanced technologies in various areas of stem cell biology, encompassing: self-renewal, differentiation, and reprogramming of different types of embryonic and adult stem cells, as well as regeneration in model organisms

* Technological tools for studying the biology of stem cells

With chapters contributed by leading authorities, this book is a hands-on reference for chemists, biologists, biochemists, bioinformaticians, clinicians, and managers involved in stem cell research. It is also an excellent text for interdisciplinary courses such as functional genomics, stem cell biology, and chemical biology.

Autor

Sheng Ding is an Associate Professor in the Departments of Chemistry and Cell Biology at the Scripps Research Institute. He is a member of the American Chemical Society, American Society for Cell Biology, and the International Society for Stem Cell Research. Dr. Ding is the author or coauthor of thirty-four papers and seventeen reviews and book chapters, in addition to being coholder of thirteen?patents.

Inhalt

Chapter 1. Embryonic Stem Cells (Crystal L. Sengstaken, Eric N.
Schulze and Qi-Long Ying).

Chapter 2. Adult Stem Cells (Lief Fenno and Chad A. Cowan).

Chapter 3. Genome-wide expression analysis technologies (John R.
Walker).

Chapter 4. Genomic cDNA and RNAi Functional Profiling and its
Potential Application to the Study of Mammalian Stem Cells (Jia
Zhang, Myleen Medina, Genevieve Welch, Deanna Shumate, Anthony
Marelli, and Anthony P. Orth).

Chapter 5. Chemical Technologies: Probing Biology with Small
Molecules (Nicolas Winssinger, Zbigniew Pianowski, and Sofia
Barluenga).

Chapter 6. Protein Characterization by Biological Mass
Spectrometry (Venkateshwar Reddy and Eric C. Peters).

Chapter 7. Large scale genomic analysis of stem cell populations
(Jonathan D. Chesnut and Mahendra S. Rao).

Chapter 8. Exploring stem cell biology with small molecules and
functional genomics (Julie Clark, Yue Xu, Simon Hilcove, and Sheng
Ding).

Chapter 9. Regeneration Screens in Model Organisms (Chetana
Sachidanandan and Randall T Peterson).

Chapter 10. Proteomics in stem cells (Qiang Tian and W. Andy
Tao).

Produkt-Details

• Erscheint lt. Verlag: 16.4.2008
• Sprache: englisch
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
• Themenwelt: Naturwissenschaften ► Chemie
• Schlagworte: Biowissenschaften • Cell & Molecular Biology • Chemie • Chemistry • Genom • Genomforschung u. Proteomik • Genomics & Proteomics • Life Sciences • Pharmaceutical & Medicinal Chemistry • Pharmazeutische u. Medizinische Chemie • Stammzelle • Zellbiologie • Zell- u. Molekularbiologie
• ISBN-10: 0-470-19912-1 / 0470199121
• ISBN-13: 978-0-470-19912-1 / 9780470199121