LHRH and Its Analogs
Kluwer Academic Publishers (Verlag)
978-0-85200-732-7 (ISBN)
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Section I. Chemistry and Basic Reproductive Properties.- 1 Development of agonistic LHRH analogs.- 2 LHRH analogs as antiovulatory agents.- 3 LHRH agonists and antagonists containing very hydrophobic amino acids.- 4 Pharmacological regulation of pituitary LHRH receptors.- Section II. Reproductive Physiology and Pharmacology in Laboratory Animals.- 5 Biological assays utilized to characterize LHRH and its analogs.- 6 Male contraceptive potential of nafarelin acetate assessed in the dog.- 7 Male fertility control with an LHRH agonist: primate studies.- 8 LHRH agonists for control of female fertility: primate studies.- 9 LHRH antagonists in rhesus and cynomolgus monkeys.- 10 LHRH antagonists in females.- 11 Biological evaluation of a highly potent LHRH antagonist.- 12 LHRH antagonists for male contraception.- Section III. Extrahypophysial Parameters.- 13 Direct antigonadal actions of LHRH.- 14 Direct gonadal stimulation with LHRH.- 15 Antisteroidal actions of LHRH agonists.- Section IV. Contraception in Women.- 16 LHRH agonists for female contraception.- 17 Postcoital contraception with intranasal buserelin.- 18 Antifertility by discontinuous treatment with buserelin in women.- 19 Risks and benefits of LHRH agonists as antifertility agents.- Section V. Contraception in Men.- 20 Effects of nafarelin acetate in men.- 21 Antifertility effects of an LHRH agonist in men.- Section VI. Human Therapeutic Applications.- 22 LHRH therapy for hypogonadotropic hypogonadal men.- 23 Correction of infertility with LHRH agonists in the male.- 24 LHRH analog therapy of precocious puberty.- 25 LHRH analogs for human mammary carcinoma.- 26 Buserelin therapy for prostatic carcinoma.- 27 Leuprolide therapy for prostatic carcinoma.- Section VII. Diagnostic Applications of Lhrh.- 28 Diagnostic uses of LHRH.- Section VIII. Applications in Animals.- 29 Actions of LHRH and its analogs in lower vertebrates.- 30 LHRH and analogs in relation to livestock.- Section IX. Metabolic Parameters.- 31 Enzymatic degradation of LHRH and analogs.- 32 Metabolism of [d-Trp6]LHRH.- 33 Absorption and metabolism of LHRH and analogs.- Section X. Perspectives.- 34 Prospects for LHRH analogs as contraceptives.- 35 The therapeutic potential of LHRH and LHRH analogs.- 36 Epilog.- J. J. Nestor Jr..
Erscheint lt. Verlag | 31.7.1984 |
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Reihe/Serie | Advances in Reproductive Health Care ; 1 |
Zusatzinfo | 500 p. |
Verlagsort | Dordrecht |
Sprache | englisch |
Gewicht | 930 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Gynäkologie / Geburtshilfe |
Medizinische Fachgebiete ► Innere Medizin ► Diabetologie | |
ISBN-10 | 0-85200-732-9 / 0852007329 |
ISBN-13 | 978-0-85200-732-7 / 9780852007327 |
Zustand | Neuware |
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