Medicinal Chemistry (eBook)

An Introduction

Gareth Thomas (Autor)

eBook Download: PDF

2008 | 2. Auflage
646 Seiten
Wiley (Verlag)
978-0-470-51830-4 (ISBN)

Infos

Medicinal Chemistry: An Introduction, Second Edition provides a comprehensive, balanced introduction to this evolving and multidisciplinary area of research. Building on the success of the First Edition, this edition has been completely revised and updated to include the latest developments in the field. Written in an accessible style, Medicinal Chemistry: An Introduction, Second Edition carefully explains fundamental principles, assuming little in the way of prior knowledge. The book focuses on the chemical principles used for drug discovery and design covering physiology and biology where relevant. It opens with a broad overview of the subject with subsequent chapters examining topics in greater depth. From the reviews of the First Edition: "e;It contains a wealth of information in a compact form"e; ANGEWANDTE CHEMIE, INTERNATIONAL EDITION "e;Medicinal Chemistry is certainly a text I would chose to teach from for undergraduates. It fills a unique niche in the market place."e; PHYSICAL SCIENCES AND EDUCATIONAL REVIEWS

Autor

Dr Gareth Thomas, The University of Portsmouth, UK.

Inhalt

Preface

Acknowledgements.

Abbreviations.

Chapter 1. An Introduction to Drugs, their Action and Discovery.

Chapter 2. Drug Structure and Solubility.

Chapter 3. Structure-activity and quantitative structures relationships.

Chapter 4. Computer aided drug design.

Chapter 5. Combinatorial Chemistry.

Chapter 6. Drugs from natural sources.

Chapter 7. Biological Membranes.

Chapter 8. Receptors and Messengers.

Chapter 9. Enzymes.

Chapter 10. Nucleic Acids.

Chapter 11. Pharmacokinetics.

Chapter 12. Drug metabolism.

Chapter 13. Complexes and chelating agents.

Chapter 14. Nitric oxide.

Chapter 15. An Introduction to drug and analogue synthesis.

Chapter 16. Drug Development and Production.

Selective further reading.

Answers to Questions.

Index.

Rezensionen

"The many strengths of this introductory text include its seamless integration of biochemistry and pharmacology to direct drug discovery." (Journal of Medicinal Chemistry, September 2008)

Produkt-Details

• Erscheint lt. Verlag: 13.10.2008
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Naturwissenschaften ► Chemie
• Themenwelt: Technik
• Schlagworte: Chemie • Chemistry • Klinische Chemie • Medizinische Chemie • Pharmaceutical & Medicinal Chemistry • Pharmazeutische Chemie • Pharmazeutische u. Medizinische Chemie
• ISBN-10: 0-470-51830-8 / 0470518308
• ISBN-13: 978-0-470-51830-4 / 9780470518304