Antibacterial Agents (eBook)

Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications

Rosaleen Anderson, Paul W. Groundwater, Adam Todd, Alan Worsley (Autoren)

eBook Download: PDF

2012 | 1. Auflage
376 Seiten
John Wiley & Sons (Verlag)
978-1-118-32543-8 (ISBN)

Infos

Antibacterial agents act against bacterial infection either by
killing the bacterium or by arresting its growth. They do this by
targeting bacterial DNA and its associated processes, attacking
bacterial metabolic processes including protein synthesis, or
interfering with bacterial cell wall synthesis and function.

Antibacterial Agents is an essential guide to this important
class of chemotherapeutic drugs. Compounds are organised according
to their target, which helps the reader understand the mechanism of
action of these drugs and how resistance can arise. The book uses
an integrated "lab-to-clinic" approach which covers
drug discovery, source or synthesis, mode of action, mechanisms of
resistance, clinical aspects (including links to current
guidelines, significant drug interactions, cautions and
contraindications), prodrugs and future improvements.

Agents covered include:

* agents targeting DNA - quinolone, rifamycin, and nitroimidazole
antibacterial agents

* agents targeting metabolic processes - sulfonamide
antibacterial agents and trimethoprim

* agents targeting protein synthesis - aminoglycoside, macrolide
and tetracycline antibiotics, chloramphenicol, and
oxazolidinones

* agents targeting cell wall synthesis - beta-Lactam and
glycopeptide antibiotics, cycloserine, isonaizid, and
daptomycin

Antibacterial Agents will find a place on the bookshelves
of students of pharmacy, pharmacology, pharmaceutical sciences,
drug design/discovery, and medicinal chemistry, and as a bench
reference for pharmacists and pharmaceutical researchers in
academia and industry.

Autor

Professor Rosaleen Anderson, Professor of Pharmaceutical Chemistry, Sunderland Pharmacy School, University of Sunderland, UK Professor Paul Groundwater, Professor of Medicinal Chemistry, Faculty of Pharmacy, The University of Sydney, Australia Dr Adam Todd, Senior Lecturer in Pharmacy Practice, Sunderland Pharmacy School, University of Sunderland, UK Dr Alan Worsley, Principal Lecturer in Pharmacy Practice, Sunderland Pharmacy School, University of Sunderland, UK

Produkt-Details

• Erscheint lt. Verlag: 30.5.2012
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Naturwissenschaften ► Chemie
• Themenwelt: Technik
• Schlagworte: Biowissenschaften • Chemie • Chemistry • Life Sciences • Medical Science • Medizin • Medizinische Chemie • Microbiology & Virology • Mikrobiologie • Mikrobiologie u. Virologie • Pharmaceutical & Medicinal Chemistry • Pharmacology & Pharmaceutical Medicine • Pharmakologie u. Pharmazeutische Medizin • Pharmazeutische Chemie • Pharmazeutische u. Medizinische Chemie
• ISBN-10: 1-118-32543-5 / 1118325435
• ISBN-13: 978-1-118-32543-8 / 9781118325438