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Parkinson's Disease and Nonmotor Dysfunction (eBook)

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2007 | 2005
XII, 308 Seiten
Humana Press (Verlag)
978-1-59259-859-5 (ISBN)

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Parkinson's Disease and Nonmotor Dysfunction fills a major gap in the current rapidly growing body of knowledge concerning Parkinson's disease. Drs. Pfeiffer and Bodis-Wollner have correctly perceived that many nonmotor features of Parkinson's disease are given insufficient attention in the medical literature. Unfortunately, they are often also given insufficient attention by the practicing neurologists who see these patients. As recently pointed out, there is clearly much more to Parkinson's disease than depletion of the nigrostriatal dopamine system (1). Parkinson's disease (not just m- tiple system atrophy) is a multisystem disorder, both pathologically and in its clinical manifestations. This is clearly true for the various motor system abnormalities, which are not fully corrected by dopamine replacement therapy strategies, but also for the nonmotor system abnormalities that are the subject of this volume. Although recently there has been increased awareness of the cognitive, psychiatric, and sleep disorders commonly associated with Parkinson's disease, many of their manifestations remain under-recognized and their importance in managing patients is underestimated. Even less attention is paid to the myriad of other nonmotor disturbances that plague these patients. For example, among the autonomic disorders, although orthostatic hypotension is well recognized, it is usually attributed to dopaminergic medications rather than to effects of the underlying disease. Urologic disorders are also very familiar in these patients, but may not be properly understood or well managed.
Parkinson's Disease and Nonmotor Dysfunction fills a major gap in the current rapidly growing body of knowledge concerning Parkinson's disease. Drs. Pfeiffer and Bodis-Wollner have correctly perceived that many nonmotor features of Parkinson's disease are given insufficient attention in the medical literature. Unfortunately, they are often also given insufficient attention by the practicing neurologists who see these patients. As recently pointed out, there is clearly much more to Parkinson's disease than depletion of the nigrostriatal dopamine system (1). Parkinson's disease (not just m- tiple system atrophy) is a multisystem disorder, both pathologically and in its clinical manifestations. This is clearly true for the various motor system abnormalities, which are not fully corrected by dopamine replacement therapy strategies, but also for the nonmotor system abnormalities that are the subject of this volume. Although recently there has been increased awareness of the cognitive, psychiatric, and sleep disorders commonly associated with Parkinson's disease, many of their manifestations remain under-recognized and their importance in managing patients is underestimated. Even less attention is paid to the myriad of other nonmotor disturbances that plague these patients. For example, among the autonomic disorders, although orthostatic hypotension is well recognized, it is usually attributed to dopaminergic medications rather than to effects of the underlying disease. Urologic disorders are also very familiar in these patients, but may not be properly understood or well managed.

Part I. Behavioral Dysfunction in Parkinson's Disease

Depression
William J. Burke, Steven P. Wengel, and Daryl Bohac

Anxiety
Hubert H. Fernandez and Tanya Simuni

Obsessionality
Marie-Andrée Bruneau

Dementia
Patricia Kavanagh and Karen Marder

Psychosis
Eric S. Molho and Stewart A. Factor

Postsurgical Behavioral Changes
Laurie M. Rilling, John A. Lucas, and Ryan J. Uitti

Part II. Autonomic Dysfunction in Parkinson's Disease

Dysphagia
Norman A. Leopold

Gastric Dysfunction
Tanya Gurevich, Amos D. Korczyn, and Nir Giladi

Intestinal Dysfunction
Ronald F. Pfeiffer

Impaired Sexual Function
Cheryl Waters and Janice Smolowitz

Urological Dysfunction
Carlos Singer

Cardiovascular Autonomic Dysfunction
David S. Goldstein

Thermoregulatory Dysfunction
Mark S. LeDoux

Respiratory Dysfunction
Holly A. Shill

Part III. Sleep-Related Dysfunction in Parkinson's Disease

Insomnia
Maria L. Moro-de-Casillas and David E. Riley

Rapid Eye Movement Sleep Behavior Disorder
Suzanne Stevens and Cynthia Comella

Excessive Daytime Sleepiness
David Hardesty, Daryl Victor, and Steven J. Frucht

Sleep Apnea
Cheryl M. Carlucci and Robert A. Hauser

Part IV. Sensory Dysfunction in Parkinson's Disease

Visual Dysfunction
Robert L. Rodnitzky

Primary Visual and Visuocognitive Deficits
Ivan Bodis-Wollner and Andrea Antal

Olfactory Dysfunction
Sarah Furtado and Zbigniew K. Wszolek

Pain Syndromes and Disorders of Sensation
Blair Ford and Ronald F. Pfeiffer

Part V. Sensorimotor Dysfunction in Parkinson's Disease

Oculomotor Dysfunction
Parashkev Nachev and Christopher Kennard

Fatigue
Carol EwingGarber and Joseph H. Friedman

Index

Erscheint lt. Verlag 10.11.2007
Reihe/Serie Current Clinical Neurology
Current Clinical Neurology
Zusatzinfo XII, 308 p. 18 illus.
Verlagsort Totowa
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Innere Medizin
Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Schlagworte Anxiety • Apathy • Autonomic Dysfunction • Cardiovascular Autonomic Dysfunction • dementia • Dental Dysfunction • Depression • Dysfunction • dysphagia • Excessive Daytime Sleepiness • fatigue • Gastric Dysfunction • I • Impaired Sexual Function • Insomnia • Intestinal Dysf
ISBN-10 1-59259-859-5 / 1592598595
ISBN-13 978-1-59259-859-5 / 9781592598595
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