Molecular Pathology of Gynecologic Cancer (eBook)

Antonio Giordano, Alessandro Bovicelli, Robert J. Kurman (Herausgeber)

eBook Download: PDF

2007 | 2007
XIII, 226 Seiten
Humana Press (Verlag)
978-1-59745-346-2 (ISBN)

Infos

This book focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. It approaches research into the pathology and treatment of gynecologic oncology from both clinical and experimental perspectives. New insights made possible by the introduction of advanced technologies into the field are presented. This new volume will be necessary reading for clinicians and experimental researchers alike.

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Molecular Pathology of Gynecologic Cancer focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. The volume begins with an explication of the editors' hypothesis that cancer is mainly a disease of the cell cycle, based on the deregulation of the physiological process of cell reproduction. The following eleven chapters focus on specific issues in gynecologic cancers, including: a proposed model of ovarian serous carcinogenesis, molecular markers for ovarian epithelial cancer, an overview of the pathology of endometrial cancer, molecular genetic aspects of endometrial carcinoma and cervical cancer, a natural history of Human Papilloma Virus (HPV) as it relates to cervical cancer, and hereditary issues in gynecologic cancers. The concluding chapter proposes and outlines a holistic approach to the treatment of female cancer patients. This new volume in Humana's Current Clinical Oncology(TM) series will be necessary reading for clinicians and experimental researchers alike.

Inhalt

Preface 7
Contents 8
Contributors 10
Color Plates 12
I INTRODUCTION 13
The Cell Cycle and the Molecular Biology of Cancer 14
II OVARIAN CANCER 26
Ovarian Serous Carcinogenesis— A Proposed Model 27
Molecular Markers in Epithelial Ovarian Cancer 39
III ENDOMETRIAL CANCER 58
Introduction to Endometrial Cancer 59
Endometrial Carcinogenesis 81
Endometrial Carcinoma—Molecular Genetic Aspects 99
IV CERVICAL CANCER 109
Natural History of HPV Infection in Adolescents and Relationship to Cervical Cancer 110
Molecular Genetics of Cervical Cancer 119
Prevention and Treatment of Cervical Cancer by Vaccination 130
V GESTATIONAL TROPHOBLASTIC DISEASE 160
Pathogenesis of Gestational Trophoblastic Lesions 161
VI HEREDITARY ISSUES IN GYNECOLOGICAL CANCER 171
Hereditary Issues In Ovarian Cancer 172
Hereditary Factors in Endometrial Cancer 197
VII THE MULTIDISCIPLINARY THERAPEUTIC APPROACH TO GYNECOLOGICAL CANCER IN THE NEW MILLENIUM 219
The Holistic Approach to Female Cancer Patients 220
Index 223

Produkt-Details

• Erscheint lt. Verlag: 5.10.2007
• Reihe/Serie: Current Clinical Oncology
• Reihe/Serie: Current Clinical Oncology
• Zusatzinfo: XIV, 226 p. 41 illus., 6 illus. in color.
• Verlagsort: Totowa
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Gynäkologie / Geburtshilfe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Schlagworte: aging • Cancer Screening • carcinoma • classification • Laboratory
• ISBN-10: 1-59745-346-3 / 1597453463
• ISBN-13: 978-1-59745-346-2 / 9781597453462