Constitutive Activity in Receptors and Other Proteins, Part B
Academic Press Inc (Verlag)
978-0-12-381296-4 (ISBN)
This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.
Identification and characterization of Steroidogenic Factor-1 inverse agonists.
Mabrouka Doghman, Franck Madoux, Peter Hodder, and Enzo Lalli
Assessment of inverse agonism for the angiotensin II type 1 receptor
Hiroshi Akazawa, Noritaka Yasuda, Shin-ichiro Miura, Issei Komuro
Measurement of inverse agonism in BARs
Carlos Alberto Taira
Inverse agonism of antidepressants: in vitro and in vivo studies
Joel Bockaert
Differential inverse agonism at the human muscarinic M3 receptor
Paola Casarosa
Ghrelin Receptor: High Constitutive Activity and Methods for Developing Inverse Agonists.
Constance Chollet
Constitutive activity and inverse agonism at the a1a and a1b adrenergic receptor subtypes.
Susanna. Cotecchia
Measurement of inverse agonism of the cannabinoid receptor
Tung Fong
Constitutively Active Thyrotropin (TSH) and Thyrotropin-Releasing Hormone (TRH) Receptors and Their Inverse Agonists
Marvin C. Gershengorn
Inverse retinoid agonists and neutral antagonists
Hinrich Gronemeyer
?-Aminobutyric Acid Type A (GABAA) Receptor Subtype Inverse Agonists as Therapeutic Agents in Cognition
Gabriella Guerrini and Ciciani Giovanna
Assays for inverse agonists in the visual system.
Masahiro Kono
Receptor-driven identification of novel human A3 adenosine receptor antagonists as potential therapeutic agents
Silvia Paoletta, Stephanie Federico, Giampiero Spalluto and Stefano Moro
Inverse agonists of steroidogenic factor SF-1
Fabrice Piu and Andria L. Del Tredici
Methods to Measure G Protein Coupled Receptor Activity for the Identification of Inverse Agonists
Gabriel Barreda-Gómez, M.Teresa Giralt and Rafael Rodríguez-Puertas
Section II-- Novel Strategies and Techniques for Constitutive Activity and Inverse Agonism
Use of Pharmacoperones to Reveal GPCR Structural Components Associated with Receptor Activation and Trafficking
Jo Ann Janovick and P. Michael Conn
Application of large-scale transiently transfected cells to functional assays of ion channels and other proteins.
Jun Chen, Sujatha Gopalakrishnan, Marc R Lake, and Bruce R Bianchi
Quantification of RNA Editing of the Serotonin 2C Receptor (5-HT2CR) Ex Vivo
Maria Fe Lanfranco, Noelle C. Anastasio, Patricia K. Seitz, and Kathryn A. Cunningham
Strategies for isolating constitutively-active and dominant-negative pheromone receptor mutants in yeast.
Mercedes Dosil and James B. Konopka
Development of a GPR23 Cell-based ß-Lactamase Reporter Assay
Paul H. Lee and Bonnie J. Hanson
Computational Modeling of Constitutively Active Mutants of GPCRs: C5a Receptor.
Gregory V. Nikiforovich and Thomas J. Baranski
TSH receptor monoclonal antibodies with agonist, antagonist and inverse agonist activities
Jane Sanders, Ricardo Núñez Miguel, Jadwiga Furmaniak, Bernard Rees Smith
Current standards, variations and pitfalls for the determination of constitutive TSHR activity in vitro
Sandra Mueller, Holger Jaeschke, Ralf Paschke
Towards the Rational Design of Constitutively Active KCa3.1 Mutant Channels
Line Garneau, Hélène Klein, Lucie Parent, Rémy Sauvé
Fusion proteins as model systems for the analysis of constitutive GPCR activity
Erich H. Schneider, Roland Seifert
Screening for Novel Constitutively Active CXCR2 Mutants and Their Cellular Effects
Giljun Park, Tom Masi, Chang K. Choi, Heejung Kim, Jeffrey M. Becker, and Tim E. Sparer
A method for parallel solid-phase synthesis of iodinated analogues of the cannabinoid receptor type I (CB1) inverse agonist rimonabant
Alan C. Spivey and Chih-Chung Tseng
Coexpression systems as models for the analysis of constitutive GPCR activity
Roland Seifert and Erich H. Schneider
Modelling and simulation of inverse agonism dynamics
Lloyd J. Bridge
Design and Use of Constitutively Active STAT5 Constructs
Michael A. Farrar
In vitro and in vivo assays of protein kinase CK2 activity
Renaud Prudent, Céline F. Sautel, Virginie Moucadel, Béatrice Laudet, Odilhe Filhol, and Claude Cochet
| Erscheint lt. Verlag | 24.11.2010 |
|---|---|
| Reihe/Serie | Methods in Enzymology |
| Verlagsort | San Diego |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 1100 g |
| Themenwelt | Medizin / Pharmazie |
| Naturwissenschaften ► Biologie ► Biochemie | |
| ISBN-10 | 0-12-381296-8 / 0123812968 |
| ISBN-13 | 978-0-12-381296-4 / 9780123812964 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
aus dem Bereich
