Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy

Buch | Softcover

502 Seiten

2024
Academic Press Inc (Verlag)
978-0-323-96121-9 (ISBN)

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Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy discusses recently developed treatments based on molecular targets which are genetically altered in cancer cells and are essential for tumor development and survival. Considerable research effort has been devoted to the development of targeted drugs that inhibit the action of pathogenic kinases, and clinical studies performed so far have validated the positive effects of kinase inhibitors for cancer treatment. Each chapter discusses a molecular target, such as ALK2, ATR, CK, Src-Abl, EGFR, Fyn-Blk-Lyn, IGFs, and PAK1. The book's chapters are written by experts who actively work on the targets to help readers fully understand how they can be used. This is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of novel cancer therapies based on molecular targets.

Dr. Vivek Asati presently work as Associate Professor in the Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga (Punjab), India. He previously worked as research associate in the Department of Pharmaceutical Sciences, Dr H.S. Gour University, Sagar (MP). He completed his PhD from the Institute of Pharmaceutical Sciences, GGV, Bilaspur. He has both research and industry experience gained at several organizations. His research areas include computer-aided drug designing and synthesis of various small molecule inhibitors. Dr. Asati has published research papers, book chapters, reviews in various peer-reviewed journals and presented own works at several national and international conferences. He Guided several M Pharm and PhD students and published patent. Dr. Ankur Vaidya did his graduation, post-graduation and PhD from Dept. of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar (M.P.) in 2004, 2008 and 2013 respectively. Dr. Vaidya has a teaching and research experience of many years and is currently working as Asst. Professor in Faculty of Pharmacy UPUMS, Saifai, Etawah (U.P.) India. Dr. Ankur has a key research interest in discovery of new anticancer agents with novel targets and published dozens outstanding publications in various International journals. Dr Vaidya has credited as reviewer of international journals of repute in the field of Pharmaceutical sciences. Dr. Ankur has guided several postgraduate theses and was also the recipient of AICTE-NDF (National Doctorate Fellowship) fellowship for PhD research project. Dr. Vaidya has published nternational book chapters, one International book authored and 1 national book. Dr. Ankur has participated/presented in various National and International conferences.

1. Activin receptor-like kinase-2 (ALK2)
2. Ataxia telangiectasia and Rad3-related protein?(ATR)
3. Breakpoint cluster region protein (BCR-AbL)
4. Casein kinase (CK)
5. c-Src kinase/Src-Abl
6. Cyclin dependent kinase 4 and 6
7. Epidermal growth factor receptor (EGFR)
8. Fyn-Blk-Lyn
9. Insulin-like growth factor (IGFs)
10. Mitotic kinesin spindle protein (KSP/Eg5 ATPase)
11. p21-activated kinase 1 (PAK1)
12. p38 mitogen-activated protein (MAP) kinase
13. Proviral integration site for Moloney murine leukemia virus-1?(PIM-1) kinase
14. Rearranged during Transfection (RET)
15. Serine/threonine-protein kinase B-Raf
16. Tubulin polymerization
17. Tumor necrosis factor receptor associated protein 1 (TRAP1)
18. Vascular Endothelial Growth Factor Receptors (VEGFR/PDGFR)

Erscheinungsdatum	20.04.2024
Verlagsort	Oxford
Sprache	englisch
Maße	191 x 235 mm
Gewicht	450 g
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Wirtschaft ► Betriebswirtschaft / Management
ISBN-10	0-323-96121-5 / 0323961215
ISBN-13	978-0-323-96121-9 / 9780323961219
Zustand	Neuware