Biomarkers

Medical and Workplace Applications

John P. Peeters, Lawrence C. Mohr, Mortimer L. Mendelsohn (Herausgeber)

Buch | Hardcover

464 Seiten

1998
Joseph Henry Press (Verlag)
978-0-309-06422-4 (ISBN)

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What are the prospects that compound-specific or diagnostically useful biomarkers can be developed and used for the benefit of workers like these and their employers? This book addresses these questions, and explores the societal and ethical issues of using biomarkers in the workplace, military, courtroom, and other settings.

A 38-year-old man who works in a factory applying coatings reports progressive breathing difficulties. A 45-year-old woman attributes her cough to copier "fumes."

What are the prospects that compound-specific or diagnostically useful biomarkers can be developed and used for the benefit of workers like these and their employers? What promise do biomarkers of susceptibility offer for reducing risk to occupational exposures? What are the legal and ethical issues associated with the use of such biomarkers?

These questions are explored in detail in this volume, which provides a comprehensive report on current and anticipated development in the application of biomarkers.

Leading investigators present data, provide expert analyses, and make recommendations in the areas of:

Dosimetry and physical measurement of exposure.
Use of chromosome aberrations, adducts, and gene mutations as measurement of exposure and response.
Metabolic susceptibility.
Organ- and system-specific biomarkers.
What biomarkers may reveal about carcinogenesis.

The book also explores the societal and ethical issues of using biomarkers in the workplace, military, courtroom, and other settings.

Table of Contents

FRONT MATTER
I INTRODUCTION
II PHYSICAL MEASUREMENTS
III ABERRATIONS, ADDUCTS, AND MUTATIONS
IV METABOLIC SUSCEPTIBILITY
V ORGAN-AND SYSTEM-SPECIFIC BIOMARKERS
VI CARCINOGENESIS
VII SOCIETAL ASPECTS AND CONCERNS
CONTRIBUTORS
INDEX

by Mortimer L. Mendelsohn, Lawrence C. Mohr, and John P. Peeters, Editors

1 FRONT MATTER; 2 I INTRODUCTION; 3 II PHYSICAL MEASUREMENTS; 4 III ABERRATIONS, ADDUCTS, AND MUTATIONS; 5 IV METABOLIC SUSCEPTIBILITY; 6 V ORGAN-AND SYSTEM-SPECIFIC BIOMARKERS; 7 VI CARCINOGENESIS; 8 VII SOCIETAL ASPECTS AND CONCERNS; 9 CONTRIBUTORS; 10 INDEX

Erscheint lt. Verlag	8.5.1998
Verlagsort	Washington
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Arbeits- / Sozial- / Umweltmedizin
	Technik ► Umwelttechnik / Biotechnologie
	Wirtschaft
ISBN-10	0-309-06422-8 / 0309064228
ISBN-13	978-0-309-06422-4 / 9780309064224
Zustand	Neuware