Gas Chromatography and Mass Spectrometry (eBook)

A Practical Guide

Fulton G. Kitson, Barbara S. Larsen, Charles N. McEwen (Autoren)

eBook Download: PDF

1996 | 1. Auflage
381 Seiten
Elsevier Science (Verlag)
978-0-08-053232-5 (ISBN)

Infos

This guide provides, under one cover, a wealth of practical information designed to facilitate the effectiveness of the GC/MS user. Separation conditions for numerous compound types are provided along with derivatized and underivatized compounds. A section on how to interpret mass spectral data, an extensive correlation of ion masses and neutral losses with possible structures, and examples of mass spectra are provided to further aid structure determination. Also included are basic information on instrumentation, ionization methods, quantitation, tips on the operation of mass spectrometers, the best derivatization procedures for a variety of compound types, troubleshooting techniques, and a variety of other information found to be useful to the practicing user of GC/MS instrumentation. This guide would be immediately valuable to the novice as well as the experienced GC/MS user who may not have the breadth of experience covered in this book.

Key Features
* Condenses and organizes recent and essential information for new and experienced GC/MS users
* Comprehensively indexed and referenced
* Includes practical methods of analysis
* Serves as a text reference for short practical courses on the subject

Inhalt

Cover 1
Copyright Page 5
Contents 8
Acknowledgments 12
Part I: The Fundamentals of GC/MS 14
Chapter 1. What Is GC/MS? 16
Chapter 2. Interpretation of Mass Spectra 38
Chapter 3. Quantitative GC/MS 48
Part II: GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types 56
Chapter 4. Acids 58
Chapter 5. Alcohols 68
Chapter 6. Aldehydes 76
Chapter 7. Amides 82
Chapter 8. Amines 90
Chapter 9. Amino Acids 100
Chapter 10. Common Contaminants 108
Chapter 11. Drugs and Their Metabolites 110
Chapter 12. Esters 120
Chapter 13. Ethers 130
Chapter 14. Fluorinated Compounds 136
Chapter 15. Gases 152
Chapter 16. Glycols 154
Chapter 17. Halogenated Compounds (Other Than Fluorinated) 158
Chapter 18. Hydrocarbons 164
Chapter 19. Isocyanates 170
Chapter 20. Ketones 174
Chapter 21. Nitriles 180
Chapter 22. Nitroaromatics 186
Chapter 23. Nitrogen-Containing Heterocyclics 194
Chapter 24. Nucleosides (TMS Derivatives) 200
Chapter 25. Pesticides 204
Chapter 26. Phenols 214
Chapter 27. Phosphorus Compounds 218
Chapter 28. Plasticizers and Other Polymer Additives (Including Phthalates) 222
Chapter 29. Prostaglandins (MO-TMS Derivatives) 226
Chapter 30. Solvents and Their Impurities 230
Chapter 31. Steroids 234
Chapter 32. Sugars (Monosaccharides) 238
Chapter 33. Sulfur Compounds 242
Part III: Ions for Determining Unknown Structures 250
Part IV: Appendices 338
Appendix 1. Definitions of Terms Related to Gas Chromatography 340
Appendix 2. Tips for Gas Chromatography 342
Appendix 3. Derivatives Found Useful in GC/MS 348
Appendix 4. Cross-Index Chart for GC Phases 356
Appendix 5. McReynolds' Constants 358
Appendix 6. Simple GC Troubleshooting 360
Appendix 7. Definitions of Terms Related to Mass Spectrometry 364
Appendix 8. Tips and Troubleshooting for Mass Spectrometers 368
Appendix 9. Atomic Masses and Isotope Abundances 372
Appendix 10. Structurally Significant McLafferty Rearrangement Ions 374
Appendix 11. Isotope Patterns for Chlorine and Bromine 376
Appendix 12. Mixtures for Determining Mass Spectral Resolution 378
Index 382

Produkt-Details

• Erscheint lt. Verlag: 30.8.1996
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Biologie ► Ökologie / Naturschutz
• Themenwelt: Naturwissenschaften ► Chemie ► Analytische Chemie
• Themenwelt: Naturwissenschaften ► Chemie ► Physikalische Chemie
• Themenwelt: Naturwissenschaften ► Chemie ► Technische Chemie
• Themenwelt: Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• Themenwelt: Weitere Fachgebiete ► Land- / Forstwirtschaft / Fischerei
• ISBN-10: 0-08-053232-2 / 0080532322
• ISBN-13: 978-0-08-053232-5 / 9780080532325