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Parvoviruses - Jonathan Kerr, Susan Cotmore, Marshall E Bloom

Parvoviruses

Buch | Hardcover
656 Seiten
2005
Hodder Arnold (Verlag)
978-0-340-81198-6 (ISBN)
CHF 317,70 inkl. MwSt
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Presents information on various aspects of the parvoviruses. This book presents the system of parvovirus classification, as agreed by the International Committee for the Taxonomy of Viruses and includes information on the virology, molecular and cellular biology. It also describes the clinical science which underpins gene therapy applications.
This comprehensive reference work brings together for the first time information on every aspect of the parvoviruses in a single volume. It presents the new system of parvovirus classification, as agreed by the International Committee for the Taxonomy of Viruses (ICTV), and includes cutting edge information on the virology, molecular and cellular biology, immunology and clinical manifestations of infection with each known and proposed member of the family Parvoviridae. The book also describes the rapidly expanding basic and clinical science which underpins gene therapy applications using helper-dependent and helper-independent parvoviruses.



The respected editorial group has drawn together renowned contributors from around the world to produce what will undoubtedly become the standard reference on the subject. It is essential reading for clinical or research virologists and microbiologists, infectious disease specialists, and public health specialists and laboratories.

Jonathan R Kerr is the Sir Joseph Hotung Senior Lecturer in Inflammation at St George's Hospital Medical School, London, UK. Marshall E Bloom is Senior Investigator at the Laboratory of Persistent Viral Diseases & Associate Director of Rocky Mountain Laboratories, National Institutes of Health, Hamilton, MT, USA. Susan Cotmore is Senior Research Scientist at Yale University School of Medicine, New Haven, CT, USA R. Michael Linden works for the Carl C. Icahn Institute for Gene Therapy and Molecular Medicine and Department of Microbiology at Mount Sinai School of Medicine, New York, NY, USA Colin R. Parrish works at the James A. Baker Institute at Cornell University, Ithaca, NY, USA

Introduction
Part 1 - Biology of the virus family
Virus groups and evolution of the family
The rugged virion
Viral life cycles
Part 2 - Pathogenesis and biology of Parvovirus infection
Parvovirus host range, cell tropism and evolution
Immunology of human erythrovirus infection
Parvovirus oncosuppression
Part 3 - Specific parvovirus infections and associated disease
Human and primate Parvoviruses
Parvoviruses of non-primate mammals (Parvovirinae)
Parvoviruses of arthropods
Part 4 - Use of Parvoviruses as gene therapy and vaccine delivery Vectors
The biology of gene delivery
AAVs
Helper-independent parvoviruses

Erscheint lt. Verlag 25.11.2005
Zusatzinfo 140 b&w line drawings, 120 b&w halftones, 20 colour halftones
Verlagsort London
Sprache englisch
Maße 210 x 276 mm
Themenwelt Medizin / Pharmazie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Veterinärmedizin Klinische Fächer Parasitologie
ISBN-10 0-340-81198-6 / 0340811986
ISBN-13 978-0-340-81198-6 / 9780340811986
Zustand Neuware
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