Polymers for Oral Drug Delivery Technologies
Woodhead Publishing (Verlag)
978-0-443-13774-7 (ISBN)
Polymers play an important role to achieve the targeted release profile consistently of an API in vivo by various functionalities like drug protection from gastric juice, fast release and supersaturation or release within a targeted area of the GI tract.
Dr Anilkumar Parambath is Senior Manager and Head of Capsules Product R&D, ACG Capsules, Mumbai, India. Prior to this he was a Principal Investigator for Performance and Specialty Materials at Syngene International Ltd, Bangalore India, where he worked on developing various elastomers, silicones, acrylics and other polymers for biomedical applications. He completed his PhD in Chemistry (Polymer Science) at the University of Kerala, India, and spend 7 years conducting post-doctoral research at Clemson University, USA, French atomic Energy Commission (CEA), France, and the University of British Columbia, Canada. He has successfully led RnD programs of several innovation initiatives in academic and industry settings. Dr. Parambath has edited two books on polymer biomaterials in drug delivery applications, including one with Elsevier in the Woodhead Publishing in Biomaterials series, and has published many books chapters and journal articles. He has two patents to his name.
Section A. Fundamentals of Oral Drug Delivery 1. GI tract environment (e.g. gastric juice, bile salts, pH, amylases, proteases etc.) 2. GI tract motility and transport 3. Drug absorption and pre-systemic metabolism and PK modelling 4. In vitro dissolution and predictive release testing 5. Principle characteristics and specification of pharmaceutical polymers 6. Regulatory Aspects of Polymers Used and new polymers for Oral Medication Section B. Role Polymer Technology in Oral Drug Delivery 7. Classes/types of polymers used in oral delivery (natural, semi-synthetic, synthetic), their chemical structure and general functionalities 8. Role of polymers in Tableting 9. Capsule forming Polymers 10. Dry and wet Granulation 11. Matrix formers 12. Functional Polymer Coatings (IR, easy to swallow, enteric etc.) 13. Amorphous systems (e.g. HME, SD) 14. Micro/Nanoparticles 15. Taste masking polymers 16. Polymers in Orally disintegrating tablets and Orally dissolving films 17. Additive manufacturing (3D printing) 18. Mucoadhesive forms 19. Gastro-retentive forms 20. Polymer blends and additives
| Erscheinungsdatum | 05.10.2024 |
|---|---|
| Reihe/Serie | Woodhead Publishing Series in Biomaterials |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 1000 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Medizin / Pharmazie ► Pharmazie | |
| Technik | |
| ISBN-10 | 0-443-13774-9 / 0443137749 |
| ISBN-13 | 978-0-443-13774-7 / 9780443137747 |
| Zustand | Neuware |
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