Spirooxindole

Chemistry, Synthesis, Characterization and Biological Significance

Gautam Patel, Vraj R. Shah, Tuan Anh Nguyen, Kalim Deshmukh (Herausgeber)

Buch | Softcover

654 Seiten

2024
Elsevier - Health Sciences Division (Verlag)
978-0-443-22324-2 (ISBN)

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Spirooxindole: Chemistry, Synthesis, Characterization and Biological Significance examines the current state-of-the-art, recent progress, and new challenges associated with the development of spirooxindole derivatives for various medicinal applications. Owing to their exceptional properties, these compounds can be used in various fields, including chemical and pharma industries, and in clinical research. This book has chapters written by experts in several different areas. It serves as a useful reference book for scientists, industrial practitioners, graduate students, and other professionals in the field of hetrocyclic chemistry, medicinal chemistry, organic synthesis clinical research and chemical sciences. The growing interest among the academics and industrial researchers in the field of organic chemistry and medicinal chemistry is the driving force for the presentation of this edited book.

Gautam Patel obtained PG from Institute of Science and Technology for Advanced Studies and Research (ISTAR), Vallabh Vidya Nagar and Doctoral degree from the M. S. University of Baroda, India. He is the Head and an Associate Professor at the Chemistry Department, Parul Institute of Applied Science, Parul University, India. His area of specialization is organic synthesis, green chemistry, nanosciences and nanotechnology. He has 3 patents to his name. Vraj R. Shah has received his B.Sc. in Industrial Chemistry from ITM Vocational University and M.Sc. degrees in Industrial Chemistry from ITM (SLS) Baroda University, Vadodara. Following his graduation, he is currently working as a graduate research assistant at the department of Chemical and Biological Engineering at The University of Alabama, USA. He has published 5 research papers in the peer-review international journals. He has contributed 8 book chapters with peer reviewed books of international publishers. His research interest mainly focuses on organic synthesis, medicinal chemistry, computational simulations, membrane synthesis, and nanotechnology. In addition, he has also received the prestigious GCF fellowship from University of Alabama to pursue his doctoral degree. Moreover, he has also been awarded “Best young researcher presentation from Sardar Vallabhbhai Patel National Institute of Technology (SVNIT). Tuan Anh Nguyen is Senior Principal Research Scientist at the Institute for Tropical Technology, Vietnam Academy of Science and Technology, Vietnam. He received B.S. in Physics from Hanoi University in 1992, and Ph.D. in Chemistry from the Paris Diderot University (France) in 2003. He was Visiting Scientist at Seoul National University (South Korea, 2004) and University of Wollongong (Australia, 2005). He then worked as Postdoctoral Research Associate and Research Scientist in the Montana State University (USA), 2006-2009. In 2012, he was appointed as the Head of the Microanalysis Department at Institute for Tropical Technology. His research activities include smart sensors, smart networks, smart hospitals, smart cities and digital twins. He edited over 70 Elsevier, 12 CRC Press, 1 Springer, 1 RSC and 2 IGI Global books. He is Editor-In-Chief of "Kenkyu Journal of Nanotechnology & Nanoscience". Dr. Kalim Deshmukh is a Senior Researcher at the New Technologies-Research Centre, University of West Bohemia, Pilsen, Czech Republic. He has over 15 years of research experience in the field of synthesis, characterization and structure-property relationships in a wide variety of polymeric materials, polymer blends and nanocomposites for various technological applications. His research interest is mainly focused on the synthesis, characterization and property investigations of polymer nanocomposites reinforced with different nanofillers including nanoparticles and carbon allotropes such as carbon black, carbon nanotubes, graphene and its derivatives for potential electronic applications.

1. Introduction of Spirooxindole 2. Synthesis of spirooxindole and its derivatives using green and nano technology 3. Stereoselective synthesis of spirooxindole scaffold 4. Characterization techniques for synthesised spirooxindole scaffold 5. Spirooxindole as a precursor 6. Medicinal applications of Spirooxindole and its derivatives- An Introduction 7. Spirooxindole derivatives as an anti-cancer agent 8. Spirooxindole derivatives as kinase based anti-cancer agents 9. Spirooxindole derivatives as an anti-viral agent 10. Spirooxindole derivatives as an anti-bacterial agent 11. Spirooxindole derivatives as an anti-oxidant agent 12. Spirooxindole derivatives as an anti-inflammatory agent 13. Other Medicinal Applications 14. A case study of the use of spirooxindole derivatives in the novel drug discovery

Erscheinungsdatum	21.08.2024
Verlagsort	Philadelphia
Sprache	englisch
Maße	216 x 276 mm
Gewicht	450 g
Themenwelt	Technik ► Maschinenbau
ISBN-10	0-443-22324-6 / 0443223246
ISBN-13	978-0-443-22324-2 / 9780443223242
Zustand	Neuware