Introduction to the Pharmaceutical Sciences
Lippincott Williams and Wilkins (Verlag)
978-0-7817-4478-2 (ISBN)
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This unique textbook provides an introductory, yet comprehensive overview of the pharmaceutical sciences. It is the first text of its kind to pursue an interdisciplinary approach in this area of study. Readers are introduced to basic concepts related to the specific disciplines in the pharmaceutical sciences, including pharmacology, pharmaceutics, pharmacokinetics, and medicinal chemistry. In an easy-to-read writing style, the book provides readers with up-to-date information on pharmacogenomics and includes comprehensive coverage of industrial drug development and regulatory approval processes. Each chapter includes chapter outlines and critical-thinking exercises, as well as numerous tables and graphs. More than 160 illustrations complement the text.
1. Introduction 1 Section I: Basic Principles 9 2. Ionization of Drugs 11 3. Solubility and Lipophilicity 27 4. Rates of Pharmaceutical Processes 43 5. Membranes and Tissues 61 Section II: Drug Structure and Design 75 6. Drugs and Their Targets 77 7. Drug Discovery and Optimization 93 8. Transport Across Biological Barriers 109 Section III: Drug Delivery 131 9. Drug Absorption 133 10. Drug Delivery Systems 147 Section IV: Drug Disposition 161 11. Drug Distribution 163 12. Drug Excretion 179 13. Drug Metabolism 193 14. Plasma Concentration-Time Curves 213 Section V: Drug Action 227 15. Ligands and Receptors 229 16. Mechanisms of Drug Action 255 17. Dose-Response Relationships 277 Section VI: Drug Therapy 291 18. Therapeutic Variability 293 19. Drug Interactions 307 20. Pharmacogenomics 321 Section VII: Special Topics 341 21. Biopharmaceuticals 343 22. Drug Discovery, Development, and Approval 369 Index 387
| Erscheint lt. Verlag | 1.8.2006 |
|---|---|
| Zusatzinfo | 175 |
| Verlagsort | Philadelphia |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Gewicht | 862 g |
| Themenwelt | Technik |
| ISBN-10 | 0-7817-4478-4 / 0781744784 |
| ISBN-13 | 978-0-7817-4478-2 / 9780781744782 |
| Zustand | Neuware |
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