Reproducibility in Biomedical Research

Epistemological and Statistical Problems and the Future

Erwin B. Montgomery Jr. (Autor)

Buch | Softcover

464 Seiten

2024 | 2nd edition
Academic Press Inc (Verlag)
978-0-443-13829-4 (ISBN)

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Reproducibility in Biomedical Research: Epistemological and Statistical Problems, Second Edition explores the ideas and conundrums inherent in scientific research. This second edition addresses new challenges to reproducibility in biosciences, namely reproducibility of machine learning Artificial Intelligence (AI), reproducibility of translation from research to medical care, and the fundamental challenges to reproducibility. All current chapters are expanded to cover advances in the topics previously addressed. This book provides biomedical researchers with a framework to better understand the reproducibility challenges in the area. Newly introduced interactive exercises and updated case studies help students understand the fundamental concepts involved in the area.

Dr. Montgomery has been an academic neurologist for over 40 years pursuing teaching, clinical and basic research at major academic medical centers. He has authored over 120 peer reviewed journal articles (available on PubMed) and 8 books on medicine (4 on the subject of Deep Brain Stimulation). The last two have been “Reproducibility in Biomedical Research (Academic Press, 2024) and “The Ethics of Everyday Medicine (Academic Press, 2023).

1. Introduction
2. The Problem of Irreproducibility
3. Validity of Biomedical Science, Reproducibility, and Irreproducibility
4. The Logic of Certainty versus the Logic of Discovery
5. The Logic of Probability and Statistics
6. Causation, Process Metaphor, and Reductionism
7. Case Studies in Clinical Biomedical Research 8. Case Studies in Basic Biomedical Research
9. Case Studies in Computational Biomedical Research
10. Case Studies in Machine Learning Artificial Intelligence (AI)
11. Reproducibility of translation from biomedical research to clinical care
12. Chaotic and Complex Systems, Statistics, and Far-from-Equilibrium Thermodynamics
13. The Nature of the Fundamental Challenges to Reproducibility in any Knowledge Discipline
14. Epilogue
15. Appendix: Types of lack of reproducibilityility

Erscheinungsdatum	27.04.2024
Verlagsort	San Diego
Sprache	englisch
Maße	191 x 235 mm
Gewicht	450 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Biomedizin
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik
	Technik ► Medizintechnik
ISBN-10	0-443-13829-X / 044313829X
ISBN-13	978-0-443-13829-4 / 9780443138294
Zustand	Neuware