Quantum Chemistry Methods for Oncological Drugs

Eudenilson L. Albuquerque (Autor)

Buch | Softcover

302 Seiten

2024
Elsevier - Health Sciences Division (Verlag)
978-0-443-15530-7 (ISBN)

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Quantum Chemistry Methods for Oncological Drugs provides a comprehensive reference text for student, researchers, and academic staff across disciplines working in the field of Nanobiotechnology, who need to grasp the unique inter-relationship of the physical, chemical, and biological properties of oncological drugs and their interactions. It provides a theoretical/computational framework based on quantum chemistry and addresses key questions in which detailed analysis and precise predictions are always required.

The sophisticated molecular recognition of various natural biological materials has been used in the formation of a complex network of structures potentially useful for a variety of pharmaceutical applications. They offer solutions to many of the obstacles that need to be overcome, with accuracy not feasible with the technologies usually available in materials science. Important common challenges presented in this book are aspects related to the biology of cancer using our immunological checking points, specialized proteins that act as brakes in the immune system, allowing it to recognize and attack more efficiently only the cancer cells, avoiding the destruction of healthy cells as in conventional chemotherapy and radiotherapy treatments.

This book is devoted to this burgeoning area of Nanobiotechnology for oncological drugs and will be valuable in covering the new developments that have occurred in the last decade or so. It is aimed at graduate students, faculty members and other researchers in physics, chemistry, biology, pharmacology, and medicine.

Eudenilson L. Albuquerque is Professor of Physics and Biophysics, at the Department of Biophysics, UFRN, Brazil, where he served as Dean for Research and Graduate Studies (1987-1991). He has previously co-authored the books Polariton in Periodic and Quasiperiodic Structures (Elsevier, 2004) and Quantum Chemistry Simulation of Biological Molecules (Cambridge University Press, 2021).

PART I: QUANTUM CHEMISTRY: A REVIEW 1. From classical to quantum physics (draft ready) 2. Main theoretical results 3. Computational approach

PART II: IMMUNE-ONCOLOGICAL DRUGS 4. Cancer Immunotherapy 5. Immune-oncological drug Atezolizumab 6. Immune-oncological drug Nivolumab 7. Immune-oncological drug Pembrolizumab 8. Immune-oncological drug Ipilimumab 9. Optoelectronics properties

PART III: TRANSVERSE ONCOLOGICAL DRUGS 10. Introduction 11. Oncological drugs complexed with the Human Serum Albumin (draft ready) 12. Anti- Breast cancer oncological drugs 13. Anti-Prostate cancer oncological drugs

PART IV: LOOKING AHEAD 14. The future of the oncological drugs

Erscheinungsdatum	01.03.2024
Verlagsort	Philadelphia
Sprache	englisch
Maße	191 x 235 mm
Gewicht	630 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Naturwissenschaften ► Chemie ► Physikalische Chemie
	Technik
ISBN-10	0-443-15530-5 / 0443155305
ISBN-13	978-0-443-15530-7 / 9780443155307
Zustand	Neuware