Cancer Epigenetics and Nanomedicine

Targeting the Right Player via Nanotechnology

Prashant Kesharwani, Chitra Thakur (Herausgeber)

Buch | Softcover

458 Seiten

2024
Academic Press Inc (Verlag)
978-0-443-13209-4 (ISBN)

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Cancer Epigenetics and Nanomedicine: Targeting the Right Player via Nanotechnology is a complete package that provides a comprehensive and thorough understanding of the key players that modulate the various steps of carcinogenesis and malignant progression of the disease and the critical targets to be exploited for developing novel modalities of diagnosis and therapeutics.

Since epigenetic aberrations can be potentially reversed and restored to their normal state through epigenetic therapy, the book also discusses the challenges and the future of the field with the cutting-edge revelations and limitations that this research endeavor can offer, thereby helping the readers to enhance their critical thinking and adopt strategies of therapeutic importance.

Dr. Prashant Kesharwani is an assistant professor of pharmaceutics at School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 300 international publications in well-reputed journals and more than 25 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award, most prestigious “Ramanujan Fellowship Award. He actively participates in outreach and scientific dissemination for the service of the wider community. Dr. Chitra Thakur is an Assistant Professor-Research in the Department of Pathology at the Stony Brook Cancer Center, New York, USA. She is a cancer biologist and has expertise in molecular oncology, mouse models of human cancers, analyzing big data in translational research, toxicology, and epigenetics in human cancers. She is the recipient of several internationally acclaimed awards such as the “DFG German Excellence Initiative Award,, “NIH-Big Data Training for Translational Omics Research and “American Cancer Society IRG. With more than 45 research articles published in mainstream scientific journals, she has contributed significantly towards the understanding of the molecular mechanisms in human cancers. She is engrossed in cancer research, teaching, and community outreach initiatives, hence fostering the scientific community and health care professionals engaged in cancer diagnosis, and treatment.

SECTION 1 Overview of cancer, internal and external factors associated with cancer
1. Overview of cancer: Mechanisms of carcinogenesis
2. Tumor metabolism and micronutrients: New insights to target malignant tumors
3. The role of one-carbon amino acids in tumor-immune metabolism: From oncogenesis to therapy
4. Environmental causes of cancer
5. Cancer stem cells—Challenges for cancer therapies
6. Carving a therapeutic niche for metastatic cancer: Opportunities and challenges

SECTION 2 Epigenetics and its importance in cancer therapies
7. An overview of epigenetics and cancer
8. Metabolic adaptation and epigenetic modulations: Unraveling tumor plasticity under variable tumor microenvironment
9. Involvement of epigenetic modifications in cancer stem cells and chemoresistance
10. Cancer biomarkers: Where genetics meets epigenetics
11. Epigenetics approach in cancer treatment with focus on lung and breast cancer
12. Dietary components as epigenetic modifiers and their roles in cancer prevention

SECTION 3 Nanomedicine targeting epigenetic machinery in cancer therapy
13. Harnessing plant-derived biosynthetic nanomaterials for epigenetic modulation in cancer therapy
14. Nanotechnology-enhanced immunotherapy for cancer
15. Nanoparticles in metastatic cancer treatment
16. Amine-terminated dendrimers: A novel method for diagnose, control and treatment of cancer
17. Nanomedicine and epigenome: Possible health risks, benefits, and future perspectives
18. Smart cancer nanomedicine: Challenges and future opportunities

Erscheinungsdatum	21.08.2024
Verlagsort	San Diego
Sprache	englisch
Maße	191 x 235 mm
Gewicht	450 g
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Technik
ISBN-10	0-443-13209-7 / 0443132097
ISBN-13	978-0-443-13209-4 / 9780443132094
Zustand	Neuware