Cell-free Circulating Dna: Purification And Analysis Techniques

Kristina Warton, Goli Samimi (Herausgeber)

Buch | Hardcover

296 Seiten

2022
World Scientific Publishing Co Pte Ltd (Verlag)
978-981-12-4467-4 (ISBN)

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Circulating cell-free DNA is poised to transform cancer diagnosis and care; however, it carries technical challenges such as low abundance, fragmentation and sensitivity to biospecimen handling. Development of clinically useful assays hinges on understanding the unique technical aspects of working with cell-free DNA as a substrate. This book provides an in-depth summary of the technical issues impacting cell-free DNA purification from blood plasma and analysis in a cancer context, including design of PCR assays, sequencing library preparation and methylation analysis. Emerging fields such as extracellular vesicles and blood nucleases are also covered, as well as basic biology and considerations pertinent to biobanking.

Erscheinungsdatum	26.08.2022
Verlagsort	Singapore
Sprache	englisch
Themenwelt	Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
	Studium ► 2. Studienabschnitt (Klinik) ► Anamnese / Körperliche Untersuchung
	Technik ► Medizintechnik
ISBN-10	981-12-4467-7 / 9811244677
ISBN-13	978-981-12-4467-4 / 9789811244674
Zustand	Neuware