Handbook of Drug Metabolism, Third Edition

Paul G. Pearson, Larry C. Wienkers (Herausgeber)

Buch | Softcover

736 Seiten

2021 | 3rd edition
CRC Press (Verlag)
978-0-367-77976-4 (ISBN)

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This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It has been updated based on developments that have occurred in the last 5 years, with new chapters on large molecules disposition, stereo-selectivity in drug metabolism, drug transporters and metabolic activation of drugs. Some chapters have been prepared by new authors who have emerged as subject area experts in the decade that has passed since publication of the first edition.

Key Features:

Continues to be the definitive reference on drug metabolism

Covers the drug transporter field, disposition of protein therapeutics and metabolic activation of drugs

Includes the contributions of world-class experts in their respective fields

Contains the work of editors who are recognized leaders and deep content experts in the field of drug metabolism

Emphasizes new scientific and regulatory developments in the field

PAUL G. PEARSON is President and CEO, Pearson Pharma Partners, Westlake Village, California, USA. Dr. Pearson received his Ph.D. in Pharmaceutical Sciences from Aston University, Birmingham, UK. He has had an extensive and successful career in pharmaceutical science, previously serving as Vice President of Pharmacokinetics and Drug Metabolism at Amgen, Inc. and Executive Director of Preclinical Drug Metabolism at Merck & Co, Inc. He is an active member of several international and national professional organizations. Dr. Pearson has contributed to numerous peer-reviewed publications and has been an honored invited lecturer at conferences, society meetings, and symposia on drug development, drug metabolism, and drug discovery. Dr Pearson is actively engaged in the discovery and development of new human therapeutics to make a drammatic difference to the lives of patients. LARRY C. WIENKERS is Principal Scientist, Wienkers Consulting, Bainbridge Island Washington, USA. Prior to consulting, Dr Wienkers served as Vice President of Pharmacokinetics and Drug Metabolism at Amgen, Inc. and Senior Director of Pharmacokinetics, Dynamics, and Metabolism at Pfizer. He obtained his Ph.D. in Medicinal Chemistry from the University of Washington, Seattle, Washington, USA and in 2014 he was awarded the University of Washington, School of Pharmacy Distinguished Alumni Award in Pharmaceutical Science and Research. Larry is a member of several professional societies, where he has served as Chair of American Society of Pharmacology and Experimental Therapeutics Division of Drug Metabolism and in 2013 was elected as Fellow in the American Association of Pharmaceutical Scientists. Dr. Wienkers has published over 80 peer-reviewed publications and book chapters has been an invited lecturer at conferences and symposia on large and small molecule drug metabolism and drug discovery.

Fundamental Aspects of Drug Metabolism. Factors Which Affect Drug Metabolism. Technologies to Study Drug Metabolism. Applications of Metabolism Studies in Drug Discovery and Development.

Erscheinungsdatum	06.04.2021
Reihe/Serie	Drugs and the Pharmaceutical Sciences
Verlagsort	London
Sprache	englisch
Maße	178 x 254 mm
Gewicht	1324 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
Themenwelt	Technik
ISBN-10	0-367-77976-5 / 0367779765
ISBN-13	978-0-367-77976-4 / 9780367779764
Zustand	Neuware