Estimating Functional Connectivity and Topology in Large-Scale Neuronal Assemblies (eBook)

Statistical and Computational Methods

Vito Paolo Pastore (Autor)

eBook Download: PDF

2020 | 1st ed. 2021
XV, 87 Seiten
Springer International Publishing (Verlag)
978-3-030-59042-0 (ISBN)

Infos

This book describes a set of novel statistical algorithms designed to infer functional connectivity of large-scale neural assemblies. The algorithms are developed with the aim of maximizing computational accuracy and efficiency, while faithfully reconstructing both the inhibitory and excitatory functional links. The book reports on statistical methods to compute the most significant functional connectivity graph, and shows how to use graph theory to extract the topological features of the computed network. A particular feature is that the methods used and extended at the purpose of this work are reported in a fairly completed, yet concise manner, together with the necessary mathematical fundamentals and explanations to understand their application. Furthermore, all these methods have been embedded in the user-friendly open source software named SpiCoDyn, which is also introduced here. All in all, this book provides researchers and graduate students in bioengineering, neurophysiology and computer science, with a set of simplified and reduced models for studying functional connectivity in in silico biological neuronal networks, thus overcoming the complexity of brain circuits.

  

Produkt-Details

• Erscheint lt. Verlag: 6.11.2020
• Reihe/Serie: Springer Theses
• Reihe/Serie: Springer Theses
• Zusatzinfo: XV, 87 p. 43 illus., 39 illus. in color.
• Sprache: englisch
• Themenwelt: Mathematik / Informatik ► Mathematik
• Themenwelt: Medizin / Pharmazie
• Themenwelt: Technik ► Bauwesen
• Schlagworte: Analysis of Neural Networks Dynamics • Computational Models of Neural Connectivity • Computing Functional Connectivity Matrices • Correlation-based Connectivity Methods • Cross-correlation Histogram • Delayed High Order Tranfer Entropy • Emergent Neural Network Topologies • Functional Connectivity Analysis • Functional-effective Connectivity • Graph Theory Analysis of Neuronal Assemblies • Graph Theory Applications in Neuroscience • Inhibitory Connections of Multiple Neuronal Spike Trains • In vitro Neuronal Assemblies • SPICODYN • Statistical Analysis of Spike Train Data • ToolConnect • Transfer Entropy in Neuroscience
• ISBN-10: 3-030-59042-9 / 3030590429
• ISBN-13: 978-3-030-59042-0 / 9783030590420