Accounts on Sustainable Flow Chemistry (eBook)

Timothy Noël, Rafael Luque (Herausgeber)

eBook Download: PDF

2020 | 1st ed. 2020
VIII, 191 Seiten
Springer International Publishing (Verlag)
978-3-030-36572-1 (ISBN)

Infos

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience.

Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Timothy Noël, born 1982 in Aalst (Belgium), received in 2004 his MSc degree (Industrial Chemical Engineering) from the KaHo Sint-Lieven in Ghent. He then moved to Ghent University to obtain a PhD at the Laboratory for Organic and Bioorganic Synthesis under the supervision of Professor Johan Van der Eycken (2005-2009). The title of his PhD manuscript is 'Synthesis and application of chiral dienes and chiral imidates for asymmetric transition metal catalysis'. Next, he moved to Massachusetts Institute of Technology (MIT) as a Fulbright Postdoctoral Fellow with Professor Stephen L. Buchwald. At MIT, he worked on the development of new continuous-flow methods for cross-coupling chemistry at the MIT-Novartis Center for Continuous Manufacturing. In 2011, he accepted a position as an assistant professor in the research group of Professor Volker Hessel at Eindhoven University of Technology. His research interest are flow chemistry, homogeneous and heterogeneous catalysis and organic synthesis.

He received in 2011 the Incentive Award for Young Researchers from the Comité de Gestion du Bulletin des Sociétés Chimiques Belges, in 2012 a VENI award from NWO and he was also finalist of the European Young Chemist Award 2012. In 2013, he received a Marie Curie Career Integration Grant from the European Union. Since 2015, he coordinates the Marie Sk?odowska-Curie ETN program 'Photo4Future' on the development of photoredox catalysis in photomicroreactors (www.photo4future.com). In 2015, he obtained a prestigious VIDI award from NWO. And in 2016, he received the Thieme Chemistry Journal Award. He serves as an associate editor for Journal of Flow Chemistry.

Rafael Luque is Deputy Head of Department from Dpt. Quimica Organica at Universidad de Cordoba, where he graduated in 2005. Prof. Luque has a significant experience on biomass and waste valorisation practises to materials, fuels and chemicals as well as nanoscale chemistry and green engineering, with over 270 published research articles, 3 patent applications and 8 edited books as well as numerous contributions to book chapters and invited, guest, keynote and plenary lectures in scientific events worldwide. Among recent awards, Rafael received the Marie Curie Prize from Instituto Andaluz de Quimica Fina in Spain (2011), the Green Talents award from the Federal Ministry of Education and Research in Germany (2011), the TR35 Spain from Technology Review and MIT as one of the top 10 young entrepreneurs in Spain (2012) the RSC Environment, Sustainability and Energy Early Career Award (2013) from the Royal Society of Chemistry UK and the 2015 Lu Jiaxi lectureship from the College of Chemistry and Engineering in Xiamen University (China).

Inhalt

Contents 6
Preface 7
Solar Photochemistry in Flow 9
Abstract 9
1 Introduction 10
2 Historical Perspective 10
3 Solar Radiation 11
3.1 Solar Constant 11
3.2 Spectral Distribution of the Extraterrestrial Solar Irradiance 11
3.3 Spectral Distribution of the Ground Solar Irradiance 12
3.4 Diffuse Solar Radiation 15
3.5 Solar Productivity Metrics 16
4 Reactor Designs 17
4.1 Solfin 17
4.2 SOLARIS and PROPHIS 21
4.3 MPI Line-focusing Reactor 24
4.4 Sunflow and Similar Design 26
4.5 Compound Parabolic Concentrator-based Reactors (CPC) 28
4.6 Luminescent solar concentrator-photomicroreactor (LSC-PM) 29
4.7 Outlook 32
Acknowledgements 33
References 33
Supported Catalysts for Continuous Flow Synthesis 36
Abstract 36
1 Introduction 36
2 Heterogenous Catalysis in Flow 37
3 Use of Supported Organocatalysts in Heterogeneous Flow Catalysis 38
4 Use of Supported CatalystsReagents in Continuous-Flow Kinetic Resolutions 53
5 Use of Supported Organometallic Catalysts in Heterogeneous Flow Catalysis 54
6 Use of Wall-Coated Approaches in Heterogeneous Flow Catalysis 66
7 Conclusions 68
References 70
The Use of Molecular Oxygen for Liquid Phase Aerobic Oxidations in Continuous Flow 73
Abstract 73
1 Introduction 74
2 Process Aspects 76
2.1 Mass and Heat Transfer 76
2.2 Technology 77
2.3 Using Diluted O2 78
2.4 Ability to Use Pure O2 79
2.5 Scale-up and Manufacture 80
3 Homogeneous Catalysis 81
3.1 Pd-Catalyzed Reactions 81
3.2 Cu-Catalyzed Reactions 84
3.3 Miscellaneous 85
4 Heterogeneous Catalysis 87
5 Uncatalyzed Reactions 92
6 Organomagnesium and Organolithium Reagents 94
7 Membrane Technologies 95
7.1 Tube-in-Tube Reactor 96
7.2 Tube-in-Shell Reactor 99
7.3 Dual- and Triple- Channel Microreactor 99
8 Photochemistry and Singlet Oxygen 100
9 Electrochemistry 102
10 Green Solvents 103
10.1 Carbon Dioxide 104
10.2 Water 106
11 Novel Reactor Developments 107
12 Conclusion 109
Acknowledgements 110
References 110
Sustaining the Transition from a Petrobased to a Biobased Chemical Industry with Flow Chemistry 117
Abstract 117
1 Introduction 118
2 Commodity and Other Large-Scale Industrially Relevant Building Blocks 119
2.1 Solvents 119
2.1.1 Alkanes 119
2.1.2 Alcohols 120
2.1.3 Ethers 121
2.1.4 Lactones 123
2.1.5 Cyclic Carbonates 124
2.1.6 Aromatics 125
2.2 Monomers 125
2.2.1 Olefins 125
2.2.2 Diols 129
2.2.3 Lactide 131
2.2.4 FDCA 132
2.3 Other Important Olefinic Building Blocks 133
3 Specialty, Fine, and Niche Chemicals 134
3.1 Specialty Monomers 134
3.2 Building Blocks for the Agrochemical and Pharmaceutical Industries 135
3.2.1 Carbonyls 135
3.2.2 N-Heterocycles 136
3.2.3 O-Heterocycles 138
3.3 Other High Value-Added Targets 139
4 Fuels and Additives 140
4.1 Derivatives of Glycerol 140
4.2 Derivatives of Levulinic Acid 142
4.3 Derivatives of HMF and Furfural 144
5 Conclusion and Perspectives 146
Acknowledgements 146
References 146
Continuous-Flow Microreactors for Polymer Synthesis: Engineering Principles and Applications 152
Abstract 152
1 Introduction 153
2 Mass Transport Phenomena in Polymerization Processes 155
2.1 Mixing Characteristics in Homogeneous Polymerization Processes 155
2.2 Mass Transfer in Heterogeneous Polymerization Processes 162
3 Heat Transfer and Energy Dissipation in Polymerization Processes 165
4 Polymerization in Continuous-Flow Microreactors 169
4.1 Homogeneous Polymerization 169
4.1.1 Free Radical Polymerization 169
4.1.2 Living Polymerization 169
4.2 Cationic Polymerization 170
4.3 Anionic Polymerization 170
4.3.1 Controlled Radical Polymerization 171
4.4 ATRP Processes 171
4.5 RAFT Processes 172
4.6 NMP Processes 174
4.6.1 Polycondensation 174
4.7 Heterogeneous Polymerization 176
4.7.1 Free-Radical Polymerization Preparing Polymer Microspheres with Controllable Morphologies 176
4.7.2 Controlled Living Polymerization for Synthesis of Functional Polymers 178
4.7.3 Catalyzed Polymerization 180
4.7.4 Channel Clogging Issue Solved by Heterogeneous Operations 182
4.8 Photopolymerization in Microreactors 183
4.8.1 Photo-induced Radical Polymerization 184
4.8.2 PhotoRAFT Processes 186
4.8.3 Other Photopolymerization Processes in Microreactors 188
5 Challenges and Remarking Conclusions 190
Acknowledgements 191
References 191

Produkt-Details

• Erscheint lt. Verlag: 23.1.2020
• Reihe/Serie: Topics in Current Chemistry Collections
• Reihe/Serie: Topics in Current Chemistry Collections
• Zusatzinfo: VIII, 191 p. 162 illus., 95 illus. in color.
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Themenwelt: Technik
• Schlagworte: Biocatalysis • Electrochemistry • green and sustainable flow chemistry • nanomaterials syntheses • Organic Syntheses • versatile continuous flow processes and technologies
• ISBN-10: 3-030-36572-7 / 3030365727
• ISBN-13: 978-3-030-36572-1 / 9783030365721