Tobacco-Specific N-Nitrosamines Recent Advances

Roger O. McClellan (Autor)

Buch | Softcover

140 Seiten

2019
CRC Press (Verlag)
978-0-367-44857-8 (ISBN)

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This book presents critical assessments of subjects that are part of the advancing frontiers of toxicology and related basic scientific disciplines or issues that form the core of some of the most complex and intractable problems with which the toxicologist has to grapple.

McClellan, Roger O.

1. Introduction 2. Formation and Analysis of Tobacco-Specific N-Nitrosamines 3. Synthesis of Tobacco-Specific N-Nitrosamines and Their Metabolites and Results of Related Bioassays 4. Endogenous Formation of Nitrosamines and Oxidative DNA-Damaging Agents in Tobacco Users 5. Recent Studies on Mechanisms of Bioactivation and Detoxification of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK), A Tobacco-Specific Lung Carcinogen 6. Epidemiology of Cancer by Tobacco Products and the Significance of TSNA 7. The Biological Significance of Tobacco-Specific N-Nitrosamines: Smoking and Adenocarcinoma of the Lung 8. Comparative Carcinogenicity, Metabolism, Mutagenicity, and DNA Binding of 7H-Dibenzo[c,g]carhazole and Dibenz[a,j]acridine 9. Concluding Remarks

Erscheinungsdatum	03.12.2019
Verlagsort	London
Sprache	englisch
Maße	210 x 280 mm
Gewicht	453 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Naturwissenschaften ► Biologie
	Technik ► Bauwesen
	Technik ► Umwelttechnik / Biotechnologie
ISBN-10	0-367-44857-2 / 0367448572
ISBN-13	978-0-367-44857-8 / 9780367448578
Zustand	Neuware