Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics

Buch | Softcover

222 Seiten

2020
Elsevier / The Lancet (Verlag)
978-0-08-103019-6 (ISBN)

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Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book.

Allan Matte is a Senior Research Officer in the Downstream Processing Team in HHT. With over 30 years of involvement in scientific R&D, he has coauthored more than 70 original research articles, reviews, and book chapters in various areas of protein science. He has also presented at a number of national and international conferences in the areas of high-throughput structural biology and antibody purification

1. LC-MS characterization of antibody-based therapeutics: recent highlights and future prospects
2. Engineering of Protein A for improved purification of antibodies and Fc-fused proteins
3. High fidelity affinity purification of Fc-fusion molecules from product related impurities
4. Recent advances in continuous downstream processing of antibodies and related products
5. Recent advances in antibody-based monolith chromatography for therapeutic applications
6. Recent advances in harvest clarification for antibodies and related products
7. Recent advances in ultrafiltration and virus filtration for production of antibodies and related biotherapeutics
8. A roadmap for IgG-like bispecific antibody purification
9. High-throughput, parallelized and automated protein purification for therapeutic antibody development

Erscheinungsdatum	02.07.2020
Verlagsort	London
Sprache	englisch
Maße	191 x 235 mm
Gewicht	540 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Technik
ISBN-10	0-08-103019-3 / 0081030193
ISBN-13	978-0-08-103019-6 / 9780081030196
Zustand	Neuware