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High-Throughput Analysis in the Pharmaceutical Industry -

High-Throughput Analysis in the Pharmaceutical Industry

Perry G. Wang (Herausgeber)

Buch | Softcover
432 Seiten
2019
CRC Press (Verlag)
978-0-367-38700-6 (ISBN)
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The introduction of combinatorial chemistry technology has increased the amount of compounds generated in a year from 50 to 2000. Conventional analytical approaches simply cannot keep up. These circumstances have caused drug discovery to take on the shape of a bottleneck, like traffic through a toll booth. In order to break the bottleneck, a corresponding revolutionary improvement to the conventional methodology must happen.

Perry G. Wang

High-Throughput Sample Preparation Techniques and Their Application to Bioanalytical Protocols and Purification of Combinatorial Libraries. On-line Sample Extraction Coupled with Muliplexing Strategy to Improve Throughput. Optimizing LC/MS Equipment to Increase Throughput in Pharmaceutical Analysis. Throughput Improvement of Bioanalytical LC/MS/MS by Sharing Detector between HPLC Systems. High-Throughput Strategies for Metabolite Identification in Drug Discovery. Utilizing Microparallel Liquid Chromatography for High-Throughput Analyses in the Pharmaceutical Industry. Strategies and Techniques for Higher Throughput ADME/PK Assays. High-Throughput Analysis in Drug Metabolism During Early Drug Discovery. High-Throughput Analysis in Support of Process Chemistry and Formulation Research and Development in the Pharmaceutical Industry. Online Solid Phase Extraction LC/MS/MS for High-Throughput Bioanalytical Analysis. Applications of High-Throughput Analysis in Therapeutic Drug Monitoring. High-Throughput Quantitative Pharmaceutical Analysis in Drug Metabolism and Pharmacokinetics Using Liquid Chromatography–Mass Spectrometry. Designing High-Throughput HPLC Assays for Small and Biological Molecules. Advances in Capillary and Nano HPLC Technology for Drug Discovery and Development. High-Throughput Analysis of Complex Protein Mixtures by Mass Spectrometry. Index

Erscheinungsdatum
Verlagsort London
Sprache englisch
Maße 178 x 254 mm
Gewicht 816 g
Themenwelt Medizin / Pharmazie Pharmazie
Technik
ISBN-10 0-367-38700-X / 036738700X
ISBN-13 978-0-367-38700-6 / 9780367387006
Zustand Neuware
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