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Revival: Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants (1992)

Buch | Softcover
544 Seiten
2019
CRC Press (Verlag)
978-1-138-56018-5 (ISBN)
CHF 116,95 inkl. MwSt
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Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. With contributions on topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants, Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development.

Rhoda G. M. Wang, Ph.D., is DABT Regulatory Toxicologist Department of Pesticide Regulation California Environmental Protection Agency, Sacramento, California, USA. James B. Knaak, Ph.D, is Product Stewardship Scientist Occidental Chemical Corporation, Niagara Falls, New York, USA. Howard I. Maibach, M.D., is Professor of Dermatology Department of Dermatology University of California, San Francisco, California, USA. 

Pharmacokinetics, Metabolism, And Percutaneous Penetration Of The Skin.


Physiologically-Based Pharmacokinetic Modeling to Predict Tissue Dose and Cholinesterase Inhibition in Workers Exposed to Organophosphorus and Carbamate Pesticides


J.B. Knaak, M.A. Al-Bayati, and O.G. Raabe


The Application of Pharmacokinetic Models to Predict Target Dose


Jerry N. Blancato and Kenneth B. Bischoff


Cytochrome P450-Dependent Metabolism of Drugs and Carcinogens in Skin


Hasan Mukhtar and Rajesh Agarwal


Percutaneous Absorption


Ronald C. Wester and Howard I. Maibach


In Vitro Skin Metabolism


Robert L. Bronaugh and Steven W. Collier


Animal Models for Percutaneous Absorption


Ronald C. Wester and Howard I. Maibach


A Comparative Study of the Kinetics and Bioavailability of Pure and Soil-Absorbed Benzene, Toluene, and M-Xylene After Dermal Exposure


Mohamed S. Abdel-Rahman, Gloria A. Slowronski, and Rita M. Turkall


Prediction of Human Percutaneous Absorption with Physicochemical Data


Robert L. Bronaugh and Curtis N. Barton


Dermal Absorption of TCDD: Effect of Age


Yolanda B. Banks and Linda S. Birnbaum


Percutaneous Absorption of Chemicals from Water During Swimming and Bathing


Ronald C. Wester and Howard I. Maibach


Percutaneous Absorption of Chemicals from Soil


David A.W. Bucks and Howard I. Maibach


Route Of Exposure And Toxicological Response.


General Overview on Toxicological Responses and Routes of Chemical Exposure


Rhoda G.M. Wang


Acute Toxicity Testing by the Dermal Route


R.C. Myers and L.R. DePass


Subchronic Dermal Exposure Studies with Industrial Chemicals


David W. Hobson


The Dose Response of Percutaneous Absorption


Ronald C. Wester and Howard I. Maibach


Reproductive and Developmental Toxicity Studies by Cutaneous Administration


R. W. Tyl, R.G. York, and J.L. Schardein


Dermal Carcinogenicity Studies of Petroleum-Derived Materials


Richard H. McKee and James J. Freeman


Comparison of Results from Carcinogenicity Tests of Two Halogenated Compounds by Oral, Dermal, and Inhalation Routes


Elizabeth K. Weisburger


The Objectives and Goals of Dermal Carcinogenicity Testing of Petroleum Liquids


James J. Freeman and Richard H. McKee


Chemical Carcinogenesis in Skin: Causation, Mechanism, and Role of Oncogenes


Rajesh Agarwal and Hasan Mukhtar


Dose, Toxicity, And Risk Assessment.


Incorporating Biological Information into the Assessment of Cancer Risk to Humans Under Various Exposure Conditions and Issues Related to High Background Tumor Incidence Rates


Chao W. Chen and Kim-Chi Hoang


Phototoxicity of Topical and Systemic Agents


Francis N. Marzulli and Howard I. Maibach


Techniques for Assessing the Health Risks of Dermal Contact with Chemicals in the Environment


Dennis J. Paustenbach and Hon-Wing Leung


Interspecies Extrapolation of Toxicological Data


Curtis C. Travis


New Models In Skin Research.


Human Skin Xenografts to Athymic Rodents as a System to Study Toxins Delivered to or Through the Skin


Gerald G. Drueger and Lynn K. Pershing


The Isolated Perfused Porcine Skin Flap


J.E. Riviere


Epidemiologic Studies Of Route Of Exposure And Health Effects.


Perspectives on Assessment of Risk from Dermal Exposure to Polycyclic Aromatic Hydrocarbons


Christopher J. Borgert et al.


The Paradox of Herbicide 2, 4-D Epidemiology


Gregory G. Bond and Ralph R. Cook


A Review of Epidemiologic Studies with Regard to Routes of Exposure to Toxicants


Anthony P. Polednak

Erscheinungsdatum
Reihe/Serie CRC Press Revivals
Verlagsort London
Sprache englisch
Gewicht 454 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Dermatologie
Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
Naturwissenschaften Biologie Biochemie
Technik Bauwesen
ISBN-10 1-138-56018-9 / 1138560189
ISBN-13 978-1-138-56018-5 / 9781138560185
Zustand Neuware
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