Dosage Form Design Considerations
Academic Press Inc (Verlag)
978-0-12-814423-7 (ISBN)
Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.
1. Preformulation in drug research and pharmaceutical product development
2. Physicochemical aspects to be considered in Pharmaceutical Product Development
3. Role of physicochemical parameters on drug absorption and their Implications in Pharmaceutical Product Development
4. Physiologic Factors Related to Drug Absorption
5. Physico-chemical, pharmaceutical and biological considerations in GIT Absorption of drugs
6. Influence of Drug Properties and Routes of Drug Administration on the design of controlled release systems
7. Drug stability and degradation studies
8. First pass metabolism considerations in Pharmaceutical Product Development
9. Dissolution profile considerations during Pharmaceutical Product Development
10. Drug disposition considerations in Pharmaceutical Product Development
11. Protein and tissue binding: Implication on pharmacokinetic parameters
12. Preformulation studies of drug substances, proteins and peptides: Role in drug discovery and Pharmaceutical Product Development
13. Role of salt selection in drug discovery and development
14. Drug Complexation: Implications in drug solubilization and oral bioavailability enhancement
15. Solubility and solubilization approaches in Pharmaceutical Product Development
16. Rheology and its implications on performance of liquid dosage forms
17. Micromeritics in Pharmaceutical Product Development
18. Four stages in Pharmaceutical Product Development – Preformulation – Prototype development - Biological aspects - Scale up studies – Commercialization
19. Scale up studies in Pharmaceutical Product Development
20. Manipulation of physiological processes for Pharmaceutical Product Development
21. Impact of pharmaceutical product Quality on Clinical Efficacy
22. Formulation additives used in Pharmaceutical Products: Emphasis on regulatory perspectives and GRAS
| Erscheinungsdatum | 20.09.2018 |
|---|---|
| Reihe/Serie | Advances in Pharmaceutical Product Development and Research |
| Verlagsort | San Diego |
| Sprache | englisch |
| Maße | 191 x 235 mm |
| Gewicht | 2220 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Medizin / Pharmazie ► Pharmazie | |
| Technik ► Umwelttechnik / Biotechnologie | |
| ISBN-10 | 0-12-814423-8 / 0128144238 |
| ISBN-13 | 978-0-12-814423-7 / 9780128144237 |
| Zustand | Neuware |
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