Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 (eBook)

Susanne Zeilinger, Juan-Francisco Martín, Carlos García-Estrada (Herausgeber)

eBook Download: PDF

2015 | 2015
XI, 256 Seiten
Springer New York (Verlag)
978-1-4939-2531-5 (ISBN)

Infos

​Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.

Juan-Francisco Martín, PhD
University of León, Department of Molecular Biology, Area of Microbiology, León, Spain

Carlos García-Estrada, DVM, PhD 
Institute of Biotechnology of León (INBIOTEC), Parque Científico de León, León, Spain

Susanne Zeilinger, PhD
Vienna University of Technology, Institute of Chemical Engineering, Vienna, Austria

Inhalt

Preface Contributors Chapter 1.    Fungal Secondary Metabolites in the “OMICS” Era                     Susanne Zeilinger, Carlos García-Estrada, and Juan-Francisco Martín Chapter 2.    Key Players in the Regulation of Fungal Secondary Metabolism                     Benjamin P. Knox and Nancy P. Keller Chapter 3.    Epigenetics of Fungal Secondary Metabolism Related Genes                     Ming-Yueh Wu and Jae-Hyuk Yu Chapter 4.    Genome Mining for Fungal Secondary Metabolic Gene Clusters                     Grayson T. Wawrzyn, Mark A. Held, Sarah E. Bloch, and Claudia Schmidt-Dannert Chapter 5.    Metagenomics and Metatranscriptomics for the Exploration of Natural Products from Soil Fungi                     Irshad Ul Haq and Jan Dirk van Elsas Chapter 6.    Metabolomics and Secondary Metabolite Profiling of Filamentous Fungi                     Bernhard Kluger, Sylvia Lehner, and Rainer Schuhmacher Chapter 7.    Fungal Chemotaxonomy                     Jens C. Frisvad Chapter 8.    Endophytic Fungi as a Source of Novel Metabolites                     Fernanda O. Chagas, Andrés Mauricio Caraballo-Rodriguez, and Mônica T. Pupo Chapter 9.    Fungal Secondary Metabolism in the Light of Animal-Fungus Interactions: From Mechanism to Ecological Function                     Marko Rohlfs Chapter 10.  Fusarium Mycotoxins and Their Role in Plant-Pathogen Interactions                      Gerhard Adam, Gerlinde Wiesenberger, and Ulrich GüldenerChapter 11.  Biosynthesis and Molecular Genetics of Peptaibiotics - Fungal Peptides Containing Alpha, Alpha - Dialkyl Amino Acids                     Xiao-Yan Song, Bin-Bin Xie, Xiu-Lan Chen, Yu-Zhong Zhang 

Produkt-Details

• Erscheint lt. Verlag: 15.6.2015
• Reihe/Serie: Fungal Biology
• Reihe/Serie: Fungal Biology
• Zusatzinfo: XI, 256 p. 35 illus., 14 illus. in color.
• Verlagsort: New York
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Themenwelt: Naturwissenschaften ► Biologie ► Mykologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zellbiologie
• Themenwelt: Technik
• Schlagworte: fungal biology • Fungal Development • fungal genomics • metabolomics of fungi • Secondary Metabolism
• ISBN-10: 1-4939-2531-8 / 1493925318
• ISBN-13: 978-1-4939-2531-5 / 9781493925315