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Stem Cell Engineering

A WTEC Global Assessment

Robert M. Nerem, Jeanne Loring, Todd C. McDevitt, Sean P. Palecek, David V. Schaffer, Peter W. Zandstra (Herausgeber)

Buch | Hardcover

XXXIII, 308 Seiten

2014 | 2014
Springer International Publishing (Verlag)
978-3-319-05073-7 (ISBN)

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This book describes a global assessment of stem cell engineering research, achieved through site visits by a panel of experts to leading institutes, followed by dedicated workshops. The assessment made clear that engineers and the engineering approach with its quantitative, system-based thinking can contribute much to the progress of stem cell research and development. The increased need for complex computational models and new, innovative technologies, such as high-throughput screening techniques, organ-on-a-chip models and in vitro tumor models require an increasing involvement of engineers and physical scientists. Additionally, this book will show that although the US is still in a leadership position in stem cell engineering, Asian countries such as Japan, China and Korea, as well as European countries like the UK, Germany, Sweden and the Netherlands are rapidly expanding their investments in the field. Strategic partnerships between countries could lead to major advances of the field and scalable expansion and differentiation of stem cells. This study was funded by the National Science Foundation (NSF), the National Institutes of Health (NIH) and the National Institute of Standards and Technology (NIST).

Preface.- Executive Summary.- Introduction.- Physical and Engineering Principles in Stem Cell Research.- High-throughput Screening, Microfluidics, Biosensors and Real-time Phenotyping.- Computational Modeling and Stem Cell Engineering.- Stem Cell Bioprocessing and Biomanufacturing.- Appendix A. Delegation Biographies.- Appendix B. Site Visit Reports.- Appendix C. 'Virtual' Site Visit Reports.- Appendix D. Glossary of Abbreviations and Acronyms.

Erscheint lt. Verlag	1.7.2014
Reihe/Serie	Science Policy Reports
Zusatzinfo	XXXIII, 308 p. 63 illus., 56 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	713 g
Themenwelt	Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
Themenwelt	Technik
Schlagworte	Application of Microfluidics • Assessment of Stem Cell Engineering • biochemical engineering • Computational Stem Cell Engineering • High-throughput screening • Innovation in Stem Cell Engineering • Investment in Stem Cell Research • In Vitro Models of Issues • Organ-on-a-Chip • Regenerative Therapie • Scalable Expansion of Stem Cells • Stem Cell Biomanufacturing • Stem Cell Bioprocessing • World Technology Evaluation Center • WTEC Report on Stem Cell Engineering
ISBN-10	3-319-05073-7 / 3319050737
ISBN-13	978-3-319-05073-7 / 9783319050737
Zustand	Neuware